Effect of prebiotic on disposition and tissue residues of tylvalosin in apparently healthy and Mycoplasma gallisepticum infected broiler chickens / (Record no. 62885)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03497cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031824.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171012s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.15.Ph.D.2017.Am.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ammar Haki Salman |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of prebiotic on disposition and tissue residues of tylvalosin in apparently healthy and Mycoplasma gallisepticum infected broiler chickens / |
| Statement of responsibility, etc. | Ammar Haki Salman ; Supervised Amer Ramadan Ali Ayad , Salah Eldin Abdelhamid Mohamed Youssef , Ahmed Mohamed Galal Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير البريبايوتك على المسار الحركي و البقايا للتيلفالوسين في الدجاج السليم و المصاب بالميكوبلازما جليسيبتكم في دجاج التسمين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ammar Haki Salman , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 148 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Veterinary Pharmacology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | A study of tylvalosin pharmacokinetics was conducted in healthy, health pretreated with prebiotic, Mycoplasma gallisepticum-infected and Mycoplasma gallisepticum-infected pretreated with prebiotic broiler chickens. Tylvalosin was administered intravenously and orally as a single dose of (25 mg/kg b.wt.) to determine its concentrations in blood as well as its kinetic disposition, the oral dose was repeated for 5 consecutive days to determine the tissues residues. The serum concentration - time curve indicated a two-compartment open model. Following intravenous injection, the mean elimination half-lives (t1/2{uF062}) of (6.666±0.285, 6.501±1.143, 3.048±0.232 and 4.284±0.204 h) The apparent volume of distribution (Vd(area)) of tylvalosin was (3.802±0.148, 6.362±0.390, 0.657±0.367 and 6.080±2.928 L/Kg) with body clearance CLÝ (0.953±0.040,1.792±0.062, 1.976±0.743 and 3.592±0.532 L/kg/h) with mean of MRT was (9.314±0.407, 7.533±0.735, 1.739±0.779 and 4.853±0.388 h) in four groups, respectively. Following oral administration, tylvalosin was absorbed with (t{u00BD}Ü) of (0.963±0.045, 0.906±0.025, 0.958±0.207 and 0.956±0.030 h) with peak serum concentration (Cmax) of (1.226±0.024, 0.873±0.009, 0.0760±0.024 and 0.854±0.020 og/ml) at (tmax) of (1.723±0.041, 1.441±0.023, 1.310±0.055 and 1.472±0.025 h) and eliminated with (t{u00BD}Ý) of (3.504±0.049, 3.600±0.165, 3.862±0.103 and 3.132±0.114 h) in four groups, respectively. The systemic bioavailability of Tylvalosin (F%) following oral administration was (47.491±0.538, 52.853±0.416, 72.96±0.003 and 88.652±6.714 %) in four groups, respectively. After single intravenous and oral dose the highest level of drug was concentrated in lung tissue comparable with other tissues, and after repeated oral doses the drug was still detected in lung tissue after 196 hour of the last dose while it is not detected in other tissues |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mycoplasma gallisepticum |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pharmacokinetic |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Tylvalosin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mohamed Galal Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amer Ramadan Ali Ayad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Salah Eldin Abdelhamid Mohamed Youssef , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.15.Ph.D.2017.Am.E | 01010110072715000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.15.Ph.D.2017.Am.E | 01020110072715000 | 22.09.2023 | CD - Rom | 72715.CD |