Liver iron concentration and serum hepcidin levels in patients with beta thalassemia / (Record no. 62960)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02796cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031826.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171015s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.Ph.D.2017.Ma.L |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mariam Saad Soliman Nassim |
| 245 10 - TITLE STATEMENT | |
| Title | Liver iron concentration and serum hepcidin levels in patients with beta thalassemia / |
| Statement of responsibility, etc. | Mariam Saad Soliman Nassim ; Supervised Ilham Youssry Ibrahim , Hadeel Mohammed Seif Eldein Aly , Rania Mohamed Samy Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | مستوى الحديد بالكبد و مستوى الهبسيدين بالدم لدى مرضى انيميا البحر الابيض المتوسط |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mariam Saad Soliman Nassim , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 179 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The aim of this study was to assess serum hepcidin levels among transfusion and non transfusion dependent thalassemia patients, to radiologically evaluate iron level in different tissues, to find a correlation between serum hepcidin and the studied iron overload indices and to identify the risk factors of iron overload. Methods: Eighty six thalassemia patients (56 TDT and 30 NTDT) were all subjected to history taking, clinical examination, and laboratory testing including full blood picture, serum ferritin detected by enzyme linked fluorescent assay, serum hepcidin: detected by enzyme linked immunosorbent assay . HAMP gene polymorphisms were detected using PCR-RFLP technique. Thirty six patients had a liver MRI (15 NTDT and 22 TDT) in which the pancreas and adrenal glands were visualized in eighteen patients (12 TDT and 6 NTDT) and twenty one had a heart MRI (14 TDT and 7 NTDT). Results: In this study, mean serum hepcidin was higher among TDT patients than NTDT patients. Among our patients,16.6% did not have liver iron overload (LIC<2mg/kg dw), 38.8% had mild iron overload (LIC 2-6 mg/kg dw), and 44.4% had moderate to severe iron overload (LIC >6mg/kg dw). Out of 21 evaluated patients: 4.5% had severe cardiac siderosis (T2*<10ms), 4.5% had moderate cardiac siderosis (T2* 10-20ms) and 91% had no cardiac iron overload (T2*>21ms). 61% of the studied patients demonstrated pancreatic T2*<21ms |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepcidin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | NTDT |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TDT |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hadeel Mohammed Seif Eldein Aly , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ilham Youssry Ibrahim , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania Mohamed Samy Mohamed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.Ph.D.2017.Ma.L | 01010110073088000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.Ph.D.2017.Ma.L | 01020110073088000 | 22.09.2023 | CD - Rom | 73088.CD |