Role of novel proteomic markers (apolipoprotein A1 and apolipoprotein A4) in early detection of HCC in chronic HCV infected patients / (Record no. 62981)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02839cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031826.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171016s2016 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.33.M.Sc.2016.Yo.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Yomna Mohamed Mostafa Hasan |
| 245 10 - TITLE STATEMENT | |
| Title | Role of novel proteomic markers (apolipoprotein A1 and apolipoprotein A4) in early detection of HCC in chronic HCV infected patients / |
| Statement of responsibility, etc. | Yomna Mohamed Mostafa Hasan ; Supervised Hasan Ahmed Ali Elgarem , Hanan Hasan Fouad , Rabab Maamoun Salama |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دور الدلالات البروتيومية الحديثة (أبوليبوبروتين أ1 و أبوليبوبروتين أ4) فى الكشف المبكر لأورام الكبد فى مرضى الالتهاب الكبدى الفيروسى المزمن سى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Yomna Mohamed Mostafa Hasan , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 123 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: HCC is one of the leading causes of cancer-related deaths worldwide and the poor survival rate is largely due to late stage diagnosis. Novel proteomic markers Apo-A1 and Apo-A4 can be used in combination with other traditional markers such as AFP for an earlier and more efficient diagnosis of HCC. Aim of the work: This study was designed to detect the role of novoe proteomic markers in early detection of HCC; Apo-A1 and Apo-A4 using ELISA technique. Methods: Plasma samples were obtained from 20 HCC patients, 20 HCV-related liver cirrhosis and 20 chronic HCV patients in addition to 20 seronegative controls. Routine clinical, laboratory and ultrasonographic assessments were done. HCC was diagnosed according to AASLD (the American association for the Study of Liver Diseases) guidelines. ELISA technique was used to detect Apo-A1 and Apo-A4. RESULTS: Increased levels of Apo-A1 in HCC patients and chronic liver patients post HCV with significant difference. Decreased levels of Apo-A4 in HCC patients, Relative increase of Apo-A4 levels in chronic liver patients. Thus Apo-A1is more specific in early detection of HCC with specificity (97.5%). Concluson: Apo-A1 can be used in early detection of HCC in Chronic liver patients post HCV infection and it is more specific than Apo-A4 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Apo-A1 and Apo-A4 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatocellular carcinoma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Proteomic markers |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Hasan Fouad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hasan Ahmed Ali Elgarem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rabab Maamoun Salama , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.33.M.Sc.2016.Yo.R | 01010110073100000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.33.M.Sc.2016.Yo.R | 01020110073100000 | 22.09.2023 | CD - Rom | 73100.CD |