MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03011cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
171021s2016 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.18.Ph.D.2016.Im.U |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Iman Abdulrahman Tohamy Zanoon |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Urinary podocyte-associated mRNA profile in Egyptian type 2 diabetic patients with diabetic nephropathy / |
| Statement of responsibility, etc. |
Iman Abdulrahman Tohamy Zanoon; Supervised Mohamed Gamal Eldin Saadi , Hala Essam Eldin Kahla , Mervat Saad Elansary |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
الحمض النووى الريبوزومى الرسول المصاحب لخلايا رجلاء "البودوسايت" فى بول مرضى السكرى "من النوع الثانى" المصريين و المصابين بمرض اعتلال الكلى السكرى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Iman Abdulrahman Tohamy Zanoon , |
| Date of publication, distribution, etc. |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
171 P. : |
| Other physical details |
facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background: Microalbuminuria is still regarded as the gold standard for diagnosing of DN, however its predictive powers are very limited. Also microalbuminuria is a nonspecific indicator of many forms of kidney injury. Thus, there is a substantial need for a biomarker that may enable detection of diabetic nephropathy at an earlier stage with higher accuracy. A biomarker derived from the urine is particularly useful, as it has the advantages of being a simple, noninvasive test and is a direct conduit to the site of injury. Podocyte injury and subsequent excretion in urine play a crucial role in the pathogenesis and progression of diabetic nephropathy (DN). Quantification of messenger RNA expression in urinary sediment by real-time PCR is emerging as a noninvasive method of screening DN-associated biomarkers. Objectives: the aim of our work is to study the expression of podocyte-associated genes in urinary sediment and their relation to disease severity in type 2 diabetic Egyptian patients with diabetic nephropathy. Subjects and methods: Diabetic patients (n=60) and healthy controls (n=20) were enrolled in this study. Diabetic patients were divided- according to their urinary albumin excretion (UAE)-into a normoalbuminuria group (UAE less than 30 mg/g, n=20), a microalbuminuria group (UAE between 30 and 300 mg/g, n=20), and a macroalbuminuria group (UAE more than 300 mg/g, n=20). Relative mRNA abundance of nephrin, podocalyxin, and podocin were quantified, and correlations between target mRNAs and clinical parameters were examined |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Diabetic nephropathy |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Nephrin |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Podocyte |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hala Essam Eldin Kahla , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mervat Saad Elansary , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Gamal Eldin Saadi , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
