MARC details
000 -LEADER |
fixed length control field |
02953cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
171023s2017 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.32.M.Sc.2017.Do.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Doaa Mohamed Elabed Elgengehy |
245 10 - TITLE STATEMENT |
Title |
Systemic lupus erythematosus activity and its relation with serum beta two microglobulin level / |
Statement of responsibility, etc. |
Doaa Mohamed Elabed Elgengehy ; Supervised Nashwa Taher Allam , Abeer Mohamed Ahmed , Maha Abdelhadi Ali |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
نشاط الذئبة الحمراء و علاقته بمستوى بيتا 2 ميكروجلوبيلين بالدم |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Doaa Mohamed Elabed Elgengehy , |
Date of publication, distribution, etc. |
2017 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
105 P. : |
Other physical details |
charts ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Objective: The aim of this study is to assess beta two microglobulin (Ý2MG) level in systemic lupus erythematosus (SLE) patients and to correlate Ý2MG level with disease activity of SLE. Methods: Serum Ý2MG, assessed by enzyme linked Immunosorbent assay (ELISA), was evaluated in 40 SLE patients (their mean age of 28.5±7.9 years), and in 40 age and sex matched healthy controls. Results: Serum Ý2MG levels were found to be significantly higher in SLE patients when compared to healthy controls (<0.001). Correlation between Ý2MG with disease activity as measured by SLEDAI showed a statistically significant difference with p-value (<0.001). In the current study we found Statistical significant correlation between Ý2MG and proteinuria with p value < 0.001.We detected positive significant correlation between Ý2MG [hematuria (p<0.005), pyuria (p <0.01) and creatinine (p=0.001)]. No significant correlation between Ý2MG and arthritis (p=0.77). Ý2MG was positively correlated with ESR with p value<0.05. No significant correlation was found between Ý2MG and C3, and also between Ý2MG and CRP. Our results showed negative correlation between Ý2MG and Hb with p value <0.05. No significance between Ý2MG and disease severity measured by SLE International collaborating clinics/American college of rheumatology damage Index (SLICC/ACR). Conclusion: Serum Ý2MG is elevated in SLE especially in lupus nephritis patients. It positively correlated with disease activity index SLEDAI and with nephritis. These data suggest that the measurement of serum Ý2MG seem to be useful to assess the disease activity especially in lupus nephritis |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Beta two microglobulin |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Lupus nephritis and disease activity |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
SLE |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Abeer Mohamed Ahmed , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Maha Abdelhadi Ali , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Nashwa Taher Allam , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Samia |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |