Sex hormones, cytokines, neuroimaging and disease severity in Egyptian female patients with relapsing remitting multiple sclerosis / (Record no. 63605)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02989cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031845.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171121s2017 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.21.Ph.D.2017.Gh.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ghada Hatem Abdelaziz |
| 245 10 - TITLE STATEMENT | |
| Title | Sex hormones, cytokines, neuroimaging and disease severity in Egyptian female patients with relapsing remitting multiple sclerosis / |
| Statement of responsibility, etc. | Ghada Hatem Abdelaziz ; Supervised Forayssa Elsayed Mohammed Talaat , Noha Taha Mostafa AboKreisha , Amr Osama Mohamed Abdelmonaem |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | هرمونات النوع: السيتوكينات: التصوير العصبى و شدة المرض فى مريضات التصلب المتناثر الانتكاسى الترددى المصريات |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ghada Hatem Abdelaziz , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 210 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Multiple sclerosis is an autoimmune disease with inflammatory, demyelinating and degenerative components. It shows sexual dimorphism supported by higher prevalence among females together with the effects of pregnancy and postpartum period on course of disease and this may be due to gender differences in immune systems, environmental factors, genetic factors and sex hormones (estrogen, progesterone, androgen and prolactin). Sex hormones have immunomodulatory effects, through influencing the cytokine milieu, in addition to their neuroprotective effects. Objectives: To study sex hormones, cytokine profile, magnetic resonance imaging and disease disability in egyptian female patients with relapsing remitting multiple sclerosis (RRMS). Subjects and Methods: This study was conducted on 40 female patients with RRMS and 20 age matched controls subjected to measurements of cytokine levels (interleukin 10, 4 and tumor necrosis factor alpha), hormonal levels (estrogen, prolactin and testosterone) and magnetic resonance imaging for assessment of brain atrophy. Results: Estogen levels were positively correlated with interleukin 10, 4 levels, prolactin levels were positively correlated with interleuin 10 levels and intercaudate ratio was increased in patients than controls and was positively correlated with expanded disability stastus scale (EDSS), finally estrogen and prolactin were negatevily correlated with intercaudate ratio though not reaching statistical significance |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cytokines |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Multiple sclerosis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Sex hormones |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amr Osama Mohamed Abdelmonaem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Forayssa Elsayed Mohammed Talaat , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noha Taha Mostafa AboKreisha , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.21.Ph.D.2017.Gh.S | 01010110073508000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.21.Ph.D.2017.Gh.S | 01020110073508000 | 22.09.2023 | CD - Rom | 73508.CD |