Study on the expression level of RECK matrix metalloproteinases inhibitor in breast cancer / (Record no. 63656)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02583cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031846.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171125s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.M.Sc.2016.Mo.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mona Sultan Mohammed Ahamed |
| 245 10 - TITLE STATEMENT | |
| Title | Study on the expression level of RECK matrix metalloproteinases inhibitor in breast cancer / |
| Statement of responsibility, etc. | Mona Sultan Mohammed Ahamed ; Supervised Marvat Elsayed Mohammad , Mohamed Ali Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | كمثبط لمصفوفة الأنزيمات المحتوية علي عناصر معدنية في سرطان الثدي RECK دراسة علي مستوي تعبير |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mona Sultan Mohammed Ahamed , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 121 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Breast cancer is a leading cause of cancer-related deaths in women worldwide. The RECK metastasis suppressor gene encodes a membrane associated MMP regulator protein that is able to suppress tumor invasion and metastasis by negatively regulating MMPs involve in carcinogenesis, such as MMP-2. This research was performed to assess RECK ,MMP2 genes amplification by RT- PCR technology, and ER ,PR, HER-2/neu expression using Immunohistochemical (IHC) staining, these markers were studied in 50 breast female cancer patients. The results of this study were that RECK gene amplification, by RT-PCR was positive in 20% while MMP2 gene amplification was positive in 30% of invasive duct breast cancer and showed the MMP2 gene was significantly associated with bad prognostic parameters as lymph nodes involvement and absence of Estrogen and Progesterone receptors. RECK gene was significantly associated with favorable prognostic factors as absence of lymph nodes involvement and presence of Estrogen and progesterone receptors. Finally it could be concluded that RECK and MMP2 genes are a significant prognostic factor correlated with invasive breast cancer. RECK and MMP2 genes expression is therefore a potentially useful prognostic marker for breast cancer |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cancer breast |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MMP2 gene |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | RECK gene |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marvat El-Sayed Mohammad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Mohamed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.M.Sc.2016.Mo.S | 01010110073539000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.M.Sc.2016.Mo.S | 01020110073539000 | 22.09.2023 | CD - Rom | 73539.CD |