MARC details
000 -LEADER |
fixed length control field |
02919cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
171209s2017 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.33.Ph.D.2017.Ta.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Tarek Ahmed Moneer Abdelkhalek Ismail |
245 10 - TITLE STATEMENT |
Title |
Serum levels of cytokeratin 19 as a prognostic marker in patients with hepatocellular carcinoma on top of chronic HCV / |
Statement of responsibility, etc. |
Tarek Ahmed Moneer Abdelkhalek ; Supervised Maissa Elsaid Elraziky , Sahar Abdelaty Sharaf , Hanan Abdelhafez Hamed |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
المستوى المصلى للسيتوكيراتين ١٩ معامل تنبؤى لتطور المرض فى المرضى الذين يعانون من سرطان الكبد الأولى الناتج عن الالتهاب الكبدي المزمن الفيروسى سى |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Tarek Ahmed Moneer Abdelkhalek Ismail , |
Date of publication, distribution, etc. |
2017 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
140 P. : |
Other physical details |
charts ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Background: HCC is the sixth most common cancer worldwide and the third most common cause of cancer death. HCC constitutes 70.48% of all liver tumors among Egyptians. HCC represents the main complication of cirrhosis. The cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastro- enteropancreatic and hepatobiliary tracts. CK19 immunohistochemistry has been used successfully in thyroid tumors to recognize papillary carcinomas for some time. However, its use in the pancreas, liver, and gastrointestinal tract has only recently come to the fore. Aim: To evaluate the role of the serum level of CK19 in HCC patients as a prognostic marker. Methods: We measured the serum levels of (cytokeratin 19) in hepatocellular carcinoma patients who underwent appropriate therapeutic interventions for its hepatic focal lesions before interventions and then a month later and six months after appropriate intervention to discuss the possibility of use of this marker as predictive of progression of disease in those patients. Reslts: We demonstrated in this study that CK19 levels were significantly higher in patients with ablated focal lesions than in non ablated 1 and 6 months after intervention. Conclusion: Serum CK19 levels could be a simple, noninvasive way to predict tumor progression and evaluating treatment response and prognosis in patients with HCC amenable for intervention |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Chronic HCV |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
CK19 |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Hepatocellular carcinoma |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Hanan Abdelhafez Hamed , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Maissa Elsaid Elraziky , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Sahar Abdelaty Sharaf , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Samia |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |