Synthesis and biological evaluation of some new fused heterocyclic azine derivatives as antimicrobial agents / (Record no. 63980)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03099cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031855.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171212s2017 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.10.M.Sc.2017.Am.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amany Mohamed Gad Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis and biological evaluation of some new fused heterocyclic azine derivatives as antimicrobial agents / |
| Statement of responsibility, etc. | Amany Mohamed Gad Mohamed ; Supervised Sobhy Mohamed Gomha |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تشييد و تقييم النشاط البيولوجى لبعض مشتقاث الأزين الملتحمة غير متجانسة الحلقة الجديدة كمضاد للميكروبات |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Amany Mohamed Gad Mohamed , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 170 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In the first project: 1,3-Di(thiophen-2-yl)prop-2-en-1-one was utilized for the synthesis of 4,6- di(thiophen-2-yl)-3,4-dihydropyrimidine-2(1H)-thione and 5,7-di(thiophen-2-yl)-2-thioxo-2,3- dihydropyrido[2,3-d]pyrimidin-4(1H)-one. The latter thiones were used for the synthesis of two new series of [1,2,4]triazolo[4,3-a]pyrimidines and pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidinones via reaction with the appropriate hydrazonoyl halides using triethylamine as a basic catalyst. The mechanism of formation of the synthesized compounds was discussed and the assigned structure was established via microanalysis, spectral data (IR, 1HNMR and mass) and quantum chemistry calculations. Moreover, the newly synthesized products were evaluated for their antimicrobial activities and the results show that some derivatives have good to mild activities. Moreover, quantum chemistry calculations studies are confirming the structure of the products. In the second project: Starting with different primary aromatic amines and formaldehyde solution (37%), a series of pyrido[2',3':4,5]pyrimido[2,1-b][1,3,5]thiadiazinones was synthesized by aminomethylation of pyridopyrimidinethione via Mannich reaction in acidic conditions. Moreover, another series of pyrido[2',3:4,5]pyrimido[2,1-b][1,3]thiazinones was prepared by Micheal addition reaction of pyridopyrimidinethione to the activated double bond of a number of arylidene malononitrile and 2-(benzo[d][1,3]dioxol-5-ylmethylene)malononitrile. In addition, treatment of 2-hydrazinyl-5,7-di(thiophen-2-yl)pyrido[2,3-d]pyrimidin-4(3H)-one with the proper aldehydes, and terephthaldehyde in refluxing acetic acid in and a few drops of hydrochloric acid afforded the corresponding hydrazones derivatives, and bis-hydrazone(s), respectively |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antimicrobial agents |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fused heterocyclic azine derivatives |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Synthesis and biological evaluation |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sobhy Mohamed Gomha , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.10.M.Sc.2017.Am.S | 01010110073708000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.10.M.Sc.2017.Am.S | 01020110073708000 | 22.09.2023 | CD - Rom | 73708.CD |