MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03220cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
171217s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.32.M.Sc.2017.We.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wesam Mustafa Ismaeil |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Serum leptin in systemic lupus erythematosus patients and its correlation with disease activity and some disease parameters / |
| Statement of responsibility, etc. |
Wesam Mustafa Ismaeil ; Supervised Sahar Fakhreldin Mohammed , Mayada Ali Abdalla ,Marwa Mohammed Sheta |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
قياس مستوى الليبتين في مصل مرضى الذئبة الحمراءوعلاقته بنشاط المرض وبعض دلائله الأخرى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Wesam Mustafa Ismaeil , |
| Date of publication, distribution, etc. |
2017 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
186 P. : |
| Other physical details |
charts ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disorder with multi-organ involvement. The continuation of inflammation in lupus could be attributed to failure of the resolution process due to presence of pro- inflammatory molecules such as leptin leading to progression and flares of lupus. Objective: To evaluate the serum levels of leptin in patients with sys-temic lupus erythematosus (SLE) and correlate their levels with disease activity and some disease parameters. Methods: Forty female SLE patients and twenty healthy women were evaluated. Patients were diagnosed according to the American College of Rheumatology (ACR) revised criteria for SLE. All patients were subjected to full history taking, thorough clinical examination, assessment of disease activity using SLEDAI and some laboratory investigations including serum leptin level (pg/ml) assessed by Enzyme Linked Immunosorbent Assay (ELISA). Patients were divided into two groups, the first with active SLE and the second with inactive SLE. Patients with SLEDAI {u2265}3 were considered active. Results: There was a significant statistically difference in serum leptin levels between SLE patients and controls (6229.65 vs 2962.30 pg/ml, P< 0.001). There were significant statistical correlations of serum leptin with BMI (P<0.001) and total cholesterol (P=0.014) in SLE patients. No statistical significant difference in levels of serum leptin was noted between active and inactive SLE groups (P=0.344). There was no significant correlation between serum leptin and disease activity measured by SLEDAI in SLE patients (P=0.310) Conclusion: Patients with SLE had elevated serum leptin levels. High leptin levels didn't seem to reflect the activity of the disease assessed by SLEDAI. In addition, there were significant statistical correlations of serum leptin with BMI and total cholesterol of SLE patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
BMI |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Serum leptin |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
SLE |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Marwa Mohammed Sheta , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mayada Ali Abdalla , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Sahar Fakhreldin Mohammed , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
