The association of oligoclonal mixed cryoglobulinemia with cirrhosis in patients infected with hepatitis C virus / (Record no. 64081)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03505cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031859.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171217s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.18.Ph.D.2017.Ra.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ragab Adly Ali Ahmed |
| 245 14 - TITLE STATEMENT | |
| Title | The association of oligoclonal mixed cryoglobulinemia with cirrhosis in patients infected with hepatitis C virus / |
| Statement of responsibility, etc. | Ragab Adly Ali Ahmed ; Supervised Maher Abu Baker Alamir, Nouran Elghandour , Nagwa Roshdy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة ارتباط الكرايوجلوبيولين المحدد المنشاء و تليف الكبد فى المرضي المصابين بالالتهاب الكبدى الفيروسى -ج |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ragab Adly Ali Ahmed , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 143 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background:Estimates of the prevalence of mixed cryoglobulinemia in people with HCV infection vary widely. This is because of unfamiliarity with clinical symptoms, lead-time bias, and mishandling of specimens. The association between cryoglobulinemia and severe liver affection is a controversial issue. The aim of the present work:To determine whether a specific cryoglobulin type, type IIa and not mixed cryoglobulins in general associate with cirrhosis & its progression in patients infected with hepatitis C virus. Patients and methods:The study conducted on 80 patients infected with HCV (with and without cirrhosis). The subjects were divided into two groups: Group 1: 40 Patients infected with hepatitis C and have evidence of liver cirrhosis. Group 2: 40 Patients infected with hepatitis C without cirrhosis. Data was collected for each patient including age, sex, cryoglobulin characterization, serum HCV-RNA concentration, anti-HCV antibodies, and serum alanine transaminase.Univariate analyses were used to compare demographics, clinical and laboratory data. Differences in proportions were examined with the Chi-square test or Fisher{u2019}s exact test. An unpaired T test was used for continuous variables. All calculated P values are 2-tailed and those < 0.05 were noted. Results:the study showedthe prevalence of mixed cryoglobulinstype IIatest,which was positive in 25% of studied population (both groups), and high positive correlation was detected between the cryoglobulins positivity and presence of cirrhosis, as we found that only 5 patients (12.5%) of group 1 (patients with no evidence of cirrhosis), while it was positive in 15 patients (37.5%) of group 2 (patients with evidence of cirrhosis) which made P-value (0.01) highly statistically significant. Also, it was found that HCV- PCR was significantly elevated in group 1(patients without cirrhosis) than in group 2 with statistically significant P-value 0.01.Finally, our studydid not detect any positive correlation between mixed cryoglobulin type IIa positivity and age, sex, or ALT levels |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatitis C virus |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Liver cirrhosis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mixed cryoglobulins |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maher Abubaker Alamir , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagwa Roshdy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nouran Elghandour , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.18.Ph.D.2017.Ra.A | 01010110073845000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.18.Ph.D.2017.Ra.A | 01020110073845000 | 22.09.2023 | CD - Rom | 73845.CD |