Study of some biochemical markers in female patients with transfusion dependent Ý-thalassemia / (Record no. 64248)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02798cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031904.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171226s2017 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.Ph.D.2017.No.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Noha Sayed Hamed Awad |
| 245 10 - TITLE STATEMENT | |
| Title | Study of some biochemical markers in female patients with transfusion dependent Ý-thalassemia / |
| Statement of responsibility, etc. | Noha Sayed Hamed Awad ; Supervised Mervat Elsayed Mohamed , Mohamed Ali Eldesouky , Samir Mostafa Abdelaziz |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسه بعض الدلالات الكيميائيه الحيويه فى الأناث المصابات بأنيميا البحر المتوسط و المعتمدات على نقل الدم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Noha Sayed Hamed Awad , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 101 P. : |
| Other physical details | facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The deleterious effect of iron overload on anti-müllerian hormone (AMH) level, as a best test to investigate ovarian reserve, was evaluated in 90 female patients with thalassemia major (TM), intermedia (TI) and minor, osteoporosis detection through measurement of bone mineral density (BMD z-score) using DXA and laboratory diagnosis. Also, to investigate the effects of iron chelation therapy including deferiprone and deferoxamine in the management of transfusion-related iron overload. The present results revealed that Serum AMH level was lower in female patients with transfusion dependent Ý-thalassemia than in thalassemia minor also, Ferritin was 25 fold more in thalassemia major compared to thalassemia minor (3088.0±2497.6 ng/ml vs. 120.3±36.2 ng/ml). There was significant negative correlation of AMH with ferritin in all thalassemic females. The prevalence rate of osteoporosis, based on the WHO criteria was 3.3% in thalassemia major and the prevalence of osteopenia was 93.3% in thalassemia major and 30% in thalassemia intermedia. The present finding implied a significantly higher ferritin, higher PTH, higher osteocalcin and lower AMH in patients with thalassemia major that used deferoxamine than deferiprone. In conclusion, patients with thalassemia major and intermedia constitute a high risk group due to higher ferritin concentrations and iron overload |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Anti-Müllerian hormone |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ferritin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Osteoporosis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mervat Elsayed Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Eldesouky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samir Mostafa Abdelaziz , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.Ph.D.2017.No.S | 01010110073933000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.Ph.D.2017.No.S | 01020110073933000 | 22.09.2023 | CD - Rom | 73933.CD |