Quality assessment of polysaccharide vaccines using instrumental methods of analysis / (Record no. 64312)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02785cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031906.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171230s2017 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.03.M.Sc.2017.As.Q |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Asmaa Ramadan Hussein |
| 245 10 - TITLE STATEMENT | |
| Title | Quality assessment of polysaccharide vaccines using instrumental methods of analysis / |
| Statement of responsibility, etc. | Asmaa Ramadan Hussein ; Supervised Mostafaa Abdelaty Shehata , Mamdouh Reda Rezk , Faten Abdelaziz Fathalla |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تحديد جودة اللقاحات عديدة السكاريد باستخدام طرق التحليل الآلى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Asmaa Ramadan Hussein , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 197 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Meningococcal meningitis is a serious infection of the meninges that affects the brain membrane. Neisseria meningitidis is a potential cause to large epidemics. Meningococcal polysaccharide vaccines are available in either bivalent (A and C) or tetravalent (A, C, Y and W135). In this work, many tests were carried out to ensure safety, efficacy and quality of meningococcal AC vaccine. This was achieved through qualitative and quantitative tests as follows; vaccine vial monitor (VVM) grade is a screening testing for validity of vaccine. Polysaccharide content test is a quantitative test to determine the quantity of each serogroup. In this work polysaccharide content of polysaccharide A (PSA) will take only one day instead of two days. Molecular size distribution (MSD) is a quantitative test for the stability. It was done by using one of three proposed methods (Individual fractions method, pooling method and ELISA method). The proposed chromatographic conditions save about 7.5 hours, compared with the official method. Pooling method is easier to handle, faster, simpler, less expensive, safe, more accurate, and applicable, because of two pools were used for testing instead of using a large numbers of individual fractions test tubes, its calculations were based on calibration curve and linear equation with more accurate results, it is saving the expensive reference and reagents used in the analysis |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Instrumental method |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Instrumental methods of analysis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polysaccharide vaccines |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faten Abdelaziz Fathalla , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mamdouh Reda Rezk , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mostafaa Abdelaty Shehata , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.03.M.Sc.2017.As.Q | 01010110073951000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.03.M.Sc.2017.As.Q | 01020110073951000 | 22.09.2023 | CD - Rom | 73951.CD |