Leptin as local inflammatory marker in COPD exacerbation / (Record no. 65125)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03271cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031933.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180222s2016 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.06.M.Sc.2016.Na.L |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Naef Gumaan Salem Ba haretha |
| 245 10 - TITLE STATEMENT | |
| Title | Leptin as local inflammatory marker in COPD exacerbation / |
| Statement of responsibility, etc. | Naef Gumaan Salem Ba haretha ; Supervised Hossam Hosny Masoud , Ahmed Mahmoud Abdelhafeez , Mohamed Said Ismail |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | اللبيتن كدليل إلتهاب موضعي لمرض السدة الرئوية المستثار |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Naef Gumaan Salem Ba haretha , |
| Date of publication, distribution, etc. | 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 194 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Chest Diseases and Tuberculosis |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background : Chronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD). Leptin is a pleiotropic cytokine thought to play a role in host response to inflammation. As recent studies have shown that leptin receptors are present in the lung, this study aimed to determine if leptin is detectable in induced sputum of COPD stable and exacerbation patients if there is a relationship between sputum leptin and other inflammatory markers in serum Aim of the work: This study aimed to detect sputum leptin and serum TNF-alpha and CRP levels in COPD patients without weight loss during stable disease and acute exacerbation, and to investigate relationships between sputum leptin, serum TNF-alpha and serum CRP in COPD exacerbation.Subjects and methods: 20 stable COPD patients, 20 COPD patients with acute exacerbation and 12 control subjects participated in this study. To eliminate the effects of sex differences, all patients and controls were male. BMI, percent ideal body weight (19-29), percent , TLC, ESR and sputum leptin, serum TNF-alpha and serum CRP levels in day 0 and day 7 were measured in exacerbation and only one in stable patients and healthy individuals (control). Sputum and serum Leptin, TNF-alpha and CRP levels were measured by ELISA.Results: In chronic obstructive disease exacerbation was statistically significant difference between sputum, serum leptin TNF-Ü and CRP levels, before and after treatment. Sputum leptin and serum CRP levels were significantly higher in the patients exacerbation than in the stable patients and healthy individuals (controls). Additionally, Sputum leptin, TNF serum and CRP levels were significantly higher in the patients exacerbation than in the healthy individuals (controls). As regards the correlation between sputum, serum leptin, TNF-Ü and CRP levels with COPD stable patients and healthy individuals (control), it was found insignificant |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | COPD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Exacerbation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Leptin hormone |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mahmoud Abdelhafeez , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hossam Hosny Masoud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Said Ismail , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Enas |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.06.M.Sc.2016.Na.L | 01010110074306000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.06.M.Sc.2016.Na.L | 01020110074306000 | 22.09.2023 | CD - Rom | 74306.CD |