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Transcranial doppler assessment of cerebral perfusion in patients with severe sepsis & septic shock in pediatric ICU / (Record no. 65246)

MARC details
000 -LEADER
fixed length control field 03446cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223031937.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180303s2017 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.28.Ph.D.2017.Ah.T
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Ahmed Galal Mohamed
245 10 - TITLE STATEMENT
Title Transcranial doppler assessment of cerebral perfusion in patients with severe sepsis & septic shock in pediatric ICU /
Statement of responsibility, etc. Ahmed Galal Mohamed ; Supervised Ahmed Saadeldin Elbeleidy , Seham Awad Elsherbini , Rania Hachim Hamdi
246 15 - VARYING FORM OF TITLE
Title proper/short title إستخدام جهاز الدوبلر علي الشرايين المخية لتقييم التغذية الدموية للمخ قي الاطفال المصابين بتسمم الدم و الصدمة البكتيرية في الرعاية المركزة
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Ahmed Galal Mohamed ,
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 122 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 ## - SUMMARY, ETC.
Summary, etc. Background:Sepsis-associated encephalopathy (SAE) is one of the most common causes of delirium in intensive care units. Its pathophysiology is complex and related to numerous processes and pathways.Alterations of the cerebral blood flow (CBF) may represent a key component for the development of SAE which may be caused by cerebral vasoconstriction. Transcranial Doppler (TCD) allows real-time accurate detection of CBF. Objectives:to assess changes in cerebral hemodynamic characteristics in pediatric septic encephalopathy patients Methodology: a prospective case control study including 75 critically ill children; 45 patients were diagnosed as severe sepsis or septic shock with encephalopathy, while the other 30 critically ill patients who were neither septic nor encephalopathic served as control.Patients were examined using the TCD on the middle cerebral artery.Pulsatility (PI) and resistive (RI) indices were measured to assess the cerebrovascular resistance (CVR). Results:cerebrovascular resistance (CVR) was higher in the septic group. This is evidenced by significantly higher PI and RI in the septic encephalopathic group than controlone (P<0.01). CO2 reactivity was impaired as there was positive statistically significant correlation between both PI and RI, and PaCO2 (r=0.4, P<0.01 and r=0.374, P=0.01 respectively). The level of consciousness of the patients was assessed by FOUR score; PI was negatively correlated to FOUR score with high significance (r = -0.357, and P=0.016). This means that pulsatility index increased with the more deepening of coma. PI and RI were significantly higher in the non-survivor cases than the survivor ones (P<0.01). By using a regression analysis method; PI was an independent risk of mortality with (O.R= 257, 95%CI= 6.1-108, P<0.01) Conclusion:in pediatric patients with SAE; CVR is higher with decreased cerebral blood flow and CO2 reactivity is impaired
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Pulsatility index
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Sepsis associated encephalopathy
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Transcranial Doppler
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ahmed Saadeldin Elbeleidy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Rania Hachim Hamdi ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Seham Awad Elsherbini ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.28.Ph.D.2017.Ah.T 01010110074525000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.28.Ph.D.2017.Ah.T 01020110074525000 22.09.2023 CD - Rom 74525.CD