MARC details
000 -LEADER |
fixed length control field |
02978cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
180318s2016 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.19.05.M.Sc.2016.Mo.O |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Mohamed Magdy Mahmoud |
245 10 - TITLE STATEMENT |
Title |
Outcome of children with acute lymphoblastic leukemia treated without cranial irradiation at National Cancer Institute, Egypt / |
Statement of responsibility, etc. |
Mohamed Magdy Mahmoud ; Supervised Iman Abdelmokhales Sidhom , Amr Abdalla Salem , Omnia Kamal Elgebaly |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
نتائج علاج الأطفال المصابين باللوكيميا الليمفاوية الحادة بدون العلاج الإشعاعى الدماغى بالمعهد القومى للأورام |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Mohamed Magdy Mahmoud , |
Date of publication, distribution, etc. |
2016 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
135 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
This retrospective study included children between 1 and 18 years of age with confirmed diagnosis of acute lymphoblastic leukemia who started treatment at the National Cancer Institute, Cairo University during the period from 1st January 2010 to 31st December 2012 and they were followed up till the end of September 2016. B-cell precursor phenotype was encountered in 78.6% ofpatients, T-cell in 21.4%. According to study XV of SJCRH criteria for risk classification, 38.5% of patients were in the low risk group and 61.5% were in the standard/high risk group. At the end of the induction phase, 49 patients (26.9%) died and the remaining 133 patients (73.1%) achieved remission. The 5 years overall survival and event free survival for all 182 patients were 52% and 51.6% respectively, while the 5 years disease free survival for evaluable 133 patients at end of inducation was 72.3%. In the current study, 9 patients had initially CNS III status, only one of them had isolated CNS relapse and none of these patients received cranial irradiation as first line. In this study, we had 10 CNS relapses out of 133 evaluable patients at end of induction (7.52%), 8 were isolated CNS relapse, while 2 were combined CNS and medullary relapse. As for for prognostic factors for any CNS relapse, risk stratification was the only significant variable. The commulative incidence of any CNS relapse was 0.8%, 5.8%, 8% and 10% at 1,2,3 and 5 years respectively while the commulative incidence of isolated CNS relapse was 0.8%, 4.9%, 7% and 8.9% at 1,2,3 and 5 years respectively |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Acute lymphoblastic leukemia |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Children |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Outcome |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Amr Abdalla Salem , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Iman Abdelmokhales Sidhom , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Omnia Kamal Elgebaly , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |