MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03185cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
180407s2017 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.28.Ph.D.2017.Ha.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Haytham Ahmed Ghita |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Study of primary and secondary hepatic dysfunction in critically ill children : |
| Remainder of title |
A single center study / |
| Statement of responsibility, etc. |
Haytham Ahmed Ghita ; Supervised Hanaa Mostafa Elkaraksy , Mona Elsaid Elraziky , Seham Awad Elsherbini |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة القصور الكبدى الأولى و الثانوى لدى الأطفال فى حالة صحية حرجة : |
| Remainder of title |
دراسة من مركز واحد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Haytham Ahmed Ghita , |
| Date of publication, distribution, etc. |
2017 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
133 P. |
| Other physical details |
charts ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background and objective: The liver is a key player in critical illness. Several studies on hepatic dysfunction in critically ill adult patients proved the significant impact of hepatic dysfunction on patients{u2019} morbidity and mortality. We conducted this study to address this problem in the pediatric population. We studied the frequency, risk factors and outcomes of hepatic dysfunction in critically ill children. Study design: This is a single center prospective analytical study Patients and methods: Patients were recruited from a 10-bed pediatric intensive care unit (PICU) at Cairo University Specialized Children Hospital. All patients admitted to this PICU in the period from April to December 2015 were included. Patients were followed up until they were discharged from or died in the PICU. Hepatic dysfunction was defined as any abnormality in liver function tests. Results: One hundred and fifty-one patients were included in this study. Ten patients (6.6%) were admitted with primary hepatic dysfunction. Patients with primary hepatic dysfunction were significantly associated with mortality (p< 0.001) but did not increase the length of stay (LOS) in PICU. Forty-three patients (28.5%) acquired secondary hepatic dysfunction during their PICU stay. Several risk factors were significantly associated with secondary hepatic dysfunction: malnutrition (p= 0.03), sepsis (p<0.001), cardiovascular events (p<0.001), hypoxia (p<0.001), use of inotropes (p<0.001) and mechanical ventilation (p=0.001), while surgery was not significantly associated with hepatic dysfunction. Independent risk factors of mortality in logistic regression analysis were cardiovascular events (p=0.009), mechanical ventilation (p=0.007) and multiple organ dysfunctions (p=0.37), while sepsis was significantly associated with prolonged LOS in PICU (p=0.005) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Critically ill patients |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Hepatic dysfunction,, |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Intensive care unit |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hanaa Mostafa Elkaraksy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mona Elsaid Elraziky , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Seham Awad Elsherbini , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
