Biochemical study on the role of propolis in experimental schistosomiasis / (Record no. 65932)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02943cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223031958.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180418s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.01.M.Sc.2017.Ta.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Tamer Youssry Mahmoud |
| 245 10 - TITLE STATEMENT | |
| Title | Biochemical study on the role of propolis in experimental schistosomiasis / |
| Statement of responsibility, etc. | Tamer Youssry Mahmoud ; Supervised Amira Abdelmonem Shaheen , Sherine Maher Risk , Amany Sayed Maghraby |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة كيموحيوية علي تأثير صمغ عسل النحل في البلهارسيا التجربية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Tamer Youssry Mahmoud , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 161 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Despite the wide currently use of praziquantel (PZQ) in treatment of schistosomiasis, low cure rates have been recorded in many studies. The aim of this study was directed to evaluate the curative effect of propolis (Pp) alone or in combination with PZQ on biochemical, immunological, parasitological and histological changes associated with experimental schistosomiasis in mice. Methods: Schistosomamansoni infected mice were divided into 2 experimental sets, each of 4 subgroups: (i) untreated, (ii) treatedwith Pp/day p.ofor 4 weeks, iii) treated with PZQ p.o 2X 500mg/kg bd wt, and (iv) treated with Pp + PZQ as in group ii and iii; all treatment started on the 8th week post infection, in addition to uninfected group as control for the previous groups. Results: Treatment of infected mice with Pp although failed to eradicate the worm, it significantly reduced the hepatic granuloma number, their lymphocytic infiltration and aggregation, hepatic and splenic myeloperoxidase (MPO) activity and plasma, liver and thymus nitric oxide (NOx) levels together with normalization of plasma proteins and alleviation of oxidative stress in the examined tissues as evidenced by reduction of malondialdehyde (MDA) and normalization of glutathione (GSH). Promising results were obtained when Pp given in combination with PZQ, where the anti-schistosomal activity of PZQ was markedly potentiated with complete alleviation and amelioration of the histological and biochemical alteration associated with schistosomiasis. Conclusion: this study highlights the potential usefulness of Pp as an adjunct to PZQ in schistosomiasis |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Praziquantel |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Propolis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Schistosomiasis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amany Sayed Maghraby , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amira Abdelmonem Shaheen , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sherine Maher Risk , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.01.M.Sc.2017.Ta.B | 01010110074881000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.01.M.Sc.2017.Ta.B | 01020110074881000 | 22.09.2023 | CD - Rom | 74881.CD |