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Evaluation of serum and synovial fluid Interleukin-33 levels in patients with active rheumatoid arthritis : (Record no. 66240)

MARC details
000 -LEADER
fixed length control field 03201cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032007.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180519s2017 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.32.Ph.D.2017.Ol.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Ola Mohamed Ali Hassan
245 10 - TITLE STATEMENT
Title Evaluation of serum and synovial fluid Interleukin-33 levels in patients with active rheumatoid arthritis :
Remainder of title the association with disease activity and clinical findings /
Statement of responsibility, etc. Ola Mohamed Ali Hassan ; Supervised Ola Mohamed Ragab , Noha Ahmed Azab , Mariam Halim Yacoub
246 15 - VARYING FORM OF TITLE
Title proper/short title تقييم مستوى انترلوكين-33 في الدم والسائل الزلالي في مرضى الروماتويد المفصلي النشط :
Remainder of title العلاقة بنشاط المرض والحالة الإكلينيكية
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Ola Mohamed Ali Hassan ,
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 146 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation
520 ## - SUMMARY, ETC.
Summary, etc. Background:Cytokine-mediated immunity plays an important role in the pathogenesis of autoimmune diseases. Several studies have shown Interleukin-33 (IL-33) to be involved in the pathogenesis of various autoimmune diseases such as systemic lupus erythematosus , systemic sclerosis,ankylosing spondylitis, primary Sjogren{u2019}s syndrome and Behcet{u2019}s disease. Recent evidence suggests that IL-33, a newly found IL-1 family cytokine,exerted profound effects in human rheumatoid arthritis (RA) and experimental inflammatory arthritis. Aim of work:The aim of this study was to evaluate serum and synovial fluid IL33 levels in active RA patients and to investigate its possible association with disease activity, clinical and laboratory findings. Patients and methods: This study was conducted on 50 RA patients and 30 osteoarthritis (OA) patients serving as a control group. All patients were subjected to full history taking, clinical examination including Disease Activity Score 28 (DAS 28), laboratory investigations as well as plain radiographs of both hands and feet and chest x-ray. Bone erosion was evaluated using the modified Sharp Score (MSS). Matched serum and synovial fluid (SF) IL-33 levelswere measured by enzyme-linked immunosorbent assay. Results:Serum and synovial IL-33 levels were significantly higher in RA patients than in OA patients. Synovial IL33 level was significantly higher than the matched serum IL-33 level in RA patients. A statisticallyinsignificantassociation was found between serum and synovial IL-33 levels with ESR, CRP, tender joint count, swollen joint count, DAS28, disease duration, rheumatoid factor, anti-CCP antibody and MSS
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Interleukin-33
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term MSS
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Rheumatoid Arthritis
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mariam Halim Yacoub ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Noha Ahmed Azab ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ola Mohamed Ragab ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.32.Ph.D.2017.Ol.E 01010110075043000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.32.Ph.D.2017.Ol.E 01020110075043000 22.09.2023 CD - Rom 75043.CD