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Determination of mesenchymal stem cells origin during regenerative endodontic procedure with assessment of the ability of an induced blood clot to aid in maturogenesis of immature necrotic permanent teeth : (Record no. 66400)

MARC details
000 -LEADER
fixed length control field 03393cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180530s2017 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.09.02.Ph.D.2017.Mo.D
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Mostafa Ibrahim Negm
245 10 - TITLE STATEMENT
Title Determination of mesenchymal stem cells origin during regenerative endodontic procedure with assessment of the ability of an induced blood clot to aid in maturogenesis of immature necrotic permanent teeth :
Remainder of title A clinical & radiographic study /
Statement of responsibility, etc. Mostafa Ibrahim Negm ; Supervised Jealan Mohamed Elshafei , Nagwa Roshdy , Ghada Elhilaly Eid
246 15 - VARYING FORM OF TITLE
Title proper/short title تحديد منشأ خلايا الميزينكيم الجذعية خلال علاج الجذور التصليحي مع تقدير قابلية الجلطة الدموية المستنتجة في المساعدة علي نضوج جذر السنة الدائمة الغير ناضجة :
Remainder of title دراسة اكلينيكية و اشاعية
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Mostafa Ibrahim Negm ,
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 123 P. :
Other physical details charts , facimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University -Faculty of Oral and Dental Medicine - Department of Endodontics
520 ## - SUMMARY, ETC.
Summary, etc. The current study was conducted to determine the origin of stem cells during treatment of necrotic immature permanent teeth using blood clot regenerative endodontic procedure, and whether apical radiolucency has any negative influence on the treatment outcome both clinically and radiographically. Thirty teeth of twenty-four patients with necrotic immature permanent teeth were included in the current study which, were divided into two groups according to the presence or absence of periapical radiolucency. All patients were subjected to regenerative endodontic standardized protocol including minimal instrumentation, chemical disinfection using 1.5% NaOCl irrigant and Bimix intracanal medicament for 3 weeks. After subsidence of signs and symptoms, Bimix was removed by NaOCl irrigant followed by chelation using 17% EDTA for growth factors exposure and finally saline was dispensed inside root canals. Quantitative assessment of mesenchymal stem cells origin was conducted using molecular biology techniques, through investigating the gene expression of CD73 and CD105 using real-time RT- PCR. Saline samples were taken on sterile paper points just before bleeding induction and blood samples were taken immediately after irritation of periapical tissues using endodontic file to decide whether stem cells arise from disinfected pulp canal space or from periapical tissues delivered via bleeding induction. Comparison between the two groups showed the existence of both gene markers in both groups with and without radiolucencies as well as both saline and blood samples, however, with variable RQ values. Paired t-test was used for comparing the RQ values for both CD105 and CD73 in both saline and blood samples. In both
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Blood Clot
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Immature Necrotic Permanent Teeth
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Regenerative Endodontic Procedure
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ghada Elhilaly Eid,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Jealan Mohamed Elshafei ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Nagwa Roshdy ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.09.02.Ph.D.2017.Mo.D 01010110074858000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.09.02.Ph.D.2017.Mo.D 01020110074858000 22.09.2023 CD - Rom 74858.CD