MARC details
000 -LEADER |
fixed length control field |
03393cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
180530s2017 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.09.02.Ph.D.2017.Mo.D |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Mostafa Ibrahim Negm |
245 10 - TITLE STATEMENT |
Title |
Determination of mesenchymal stem cells origin during regenerative endodontic procedure with assessment of the ability of an induced blood clot to aid in maturogenesis of immature necrotic permanent teeth : |
Remainder of title |
A clinical & radiographic study / |
Statement of responsibility, etc. |
Mostafa Ibrahim Negm ; Supervised Jealan Mohamed Elshafei , Nagwa Roshdy , Ghada Elhilaly Eid |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
تحديد منشأ خلايا الميزينكيم الجذعية خلال علاج الجذور التصليحي مع تقدير قابلية الجلطة الدموية المستنتجة في المساعدة علي نضوج جذر السنة الدائمة الغير ناضجة : |
Remainder of title |
دراسة اكلينيكية و اشاعية |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Mostafa Ibrahim Negm , |
Date of publication, distribution, etc. |
2017 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
123 P. : |
Other physical details |
charts , facimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (Ph.D.) - Cairo University -Faculty of Oral and Dental Medicine - Department of Endodontics |
520 ## - SUMMARY, ETC. |
Summary, etc. |
The current study was conducted to determine the origin of stem cells during treatment of necrotic immature permanent teeth using blood clot regenerative endodontic procedure, and whether apical radiolucency has any negative influence on the treatment outcome both clinically and radiographically. Thirty teeth of twenty-four patients with necrotic immature permanent teeth were included in the current study which, were divided into two groups according to the presence or absence of periapical radiolucency. All patients were subjected to regenerative endodontic standardized protocol including minimal instrumentation, chemical disinfection using 1.5% NaOCl irrigant and Bimix intracanal medicament for 3 weeks. After subsidence of signs and symptoms, Bimix was removed by NaOCl irrigant followed by chelation using 17% EDTA for growth factors exposure and finally saline was dispensed inside root canals. Quantitative assessment of mesenchymal stem cells origin was conducted using molecular biology techniques, through investigating the gene expression of CD73 and CD105 using real-time RT- PCR. Saline samples were taken on sterile paper points just before bleeding induction and blood samples were taken immediately after irritation of periapical tissues using endodontic file to decide whether stem cells arise from disinfected pulp canal space or from periapical tissues delivered via bleeding induction. Comparison between the two groups showed the existence of both gene markers in both groups with and without radiolucencies as well as both saline and blood samples, however, with variable RQ values. Paired t-test was used for comparing the RQ values for both CD105 and CD73 in both saline and blood samples. In both |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Blood Clot |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Immature Necrotic Permanent Teeth |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Regenerative Endodontic Procedure |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Ghada Elhilaly Eid, |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Jealan Mohamed Elshafei , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Nagwa Roshdy , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |