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A pharmaceutical study on modified drug delivery systems containing a short acting drug / (Record no. 66638)

MARC details
000 -LEADER
fixed length control field 02058cam a2200337 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032018.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180626s2017 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.08.08.M.Sc.2017.Mi.P
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Michael Magdy Farag Abdelmalak
245 12 - TITLE STATEMENT
Title A pharmaceutical study on modified drug delivery systems containing a short acting drug /
Statement of responsibility, etc. Michael Magdy Farag Abdelmalak ; Supervised Soad A. Yehia , Nevine S. Abdelmalak
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة صيدلية عن نظم توصيل معدلة تحتوى على عقار قصير المفعول
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Michael Magdy Farag Abdelmalak ,
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 185 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
520 ## - SUMMARY, ETC.
Summary, etc. Zaleplon is a hypnotic drug indicated for the short term management of insomnia for sleep induction. Also it has shown efficacy in treatment of middle of night insomnia without hangover effects. Zaleplon undergoes an extensive hepatic first pass metabolism leaving only 30% systemically available. Its elimination half-life is I hour. ZLP belongs to BCS class II with poor solubility and high permeability. Despite being rapidly absorbed after oral adminstration, the poor aqueous solubility of ZLP limits its dissolution rate and delays its onset of action. The best achieved formula of chaper I FM5 showed optimum mucoadhesion strength (1507.12±62.238 mcg/cm²) and controlled release profile (Q₃hr= 29.06%±0.73% and Q₁₂hr= 87.24%±1.71%) with desirability {u2243} 0.7
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term bi-layered chronopatches
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Pulsatile release
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Zaleplon
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Nevine Shawky Abdelmalak ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Soad Ali Yehia ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Samia
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.08.08.M.Sc.2017.Mi.P 01010110075267000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.08.08.M.Sc.2017.Mi.P 01020110075267000 22.09.2023 CD - Rom 75267.CD