header

Histological study on effect of curcumin versus aftamed on glucocorticoid induced skin atrophy and subsequent skin abrasions in male rats / (Record no. 66982)

MARC details
000 -LEADER
fixed length control field 02988cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180807s2018 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.16.Ph.D.2018.Sa.H
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Samia Hamdy Radwan Sayed
245 10 - TITLE STATEMENT
Title Histological study on effect of curcumin versus aftamed on glucocorticoid induced skin atrophy and subsequent skin abrasions in male rats /
Statement of responsibility, etc. Samia Hamdy Radwan Sayed ; Supervised Sohair Ahmed Fawzy Tawfiq , Nagwa Abdelwahab Ahmed , Mohamed Deiaa Eldin M. Elshafie
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة هستولوجية على تأثير الكركم مقارنة بالأفتاميد على ضمور الجلد المستحدث بالجلوكوكورتيكويد و سحجات الجلد اللاحقه له فى ذكور الفئران
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Samia Hamdy Radwan Sayed ,
Date of publication, distribution, etc. 2018
300 ## - PHYSICAL DESCRIPTION
Extent 196 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Histology
520 ## - SUMMARY, ETC.
Summary, etc. This study aimed to evaluate the possible therapeutic effects of curcumin versus aftamed gel on glucocorticoid-induced skin atrophy, as well as on the subsequently induced abrasion wounds. Forty two adult male albino rats were divided into 4 groups: Group1 (Control group) of 6 rats. Group II (steroid-exposed Group) of 12 rats subdivided equally into two subgroups IIA (subjected to clobetasol propionate cream) and IIB (subsequently exposed to skin abrasion). Group III (curcumin-treated Group) of 12 rats were subdivided equally into two subgroups IIIA and IIIB. Group IV (Aftamed-treated group) of 12 rats subdivided equally into two subgroups IVA and IVB. Skin biopsies were taken from the dorsum of rats 12th days from the stoppage of clobetasol propionate application. Sections were stained with hematoxylin and eosin, Masson's trichrome and immunohistochemichal stain for PCNA and CK19. Epidermal thicknesses, mean area percent of collagen fibers and mean number of PCNA and CK19 immunopositive cells were measured. Steroid-exposed group showed thinning of epidermal and dermal layers with marked decrease in numbers of hair follicles and sebaceous glands with delay in wound healing. Increased epidermal thickness and reorganized dermal structural elements with increased PCNA and CK19 immunopositive cells are more obvious in curcumin than aftamed treated group. These findings suggest that topical application of curcumin had more improving effect on skin and its abrasions rather than aftamed gel
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Skin atrophy
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Topical steroids
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Wound
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohamed Deiaa Eldin Mohamed Elshafie ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Nagwa Abdelwahab Ahmed ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Sohair Ahmed Fawzy Tawfiq ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Samia
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.16.Ph.D.2018.Sa.H 01010110075481000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.16.Ph.D.2018.Sa.H 01020110075481000 22.09.2023 CD - Rom 75481.CD