Histological study on effect of curcumin versus aftamed on glucocorticoid induced skin atrophy and subsequent skin abrasions in male rats / (Record no. 66982)
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000 -LEADER | |
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fixed length control field | 02988cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 180807s2018 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.11.16.Ph.D.2018.Sa.H |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Samia Hamdy Radwan Sayed |
245 10 - TITLE STATEMENT | |
Title | Histological study on effect of curcumin versus aftamed on glucocorticoid induced skin atrophy and subsequent skin abrasions in male rats / |
Statement of responsibility, etc. | Samia Hamdy Radwan Sayed ; Supervised Sohair Ahmed Fawzy Tawfiq , Nagwa Abdelwahab Ahmed , Mohamed Deiaa Eldin M. Elshafie |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | دراسة هستولوجية على تأثير الكركم مقارنة بالأفتاميد على ضمور الجلد المستحدث بالجلوكوكورتيكويد و سحجات الجلد اللاحقه له فى ذكور الفئران |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Samia Hamdy Radwan Sayed , |
Date of publication, distribution, etc. | 2018 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 196 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Histology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | This study aimed to evaluate the possible therapeutic effects of curcumin versus aftamed gel on glucocorticoid-induced skin atrophy, as well as on the subsequently induced abrasion wounds. Forty two adult male albino rats were divided into 4 groups: Group1 (Control group) of 6 rats. Group II (steroid-exposed Group) of 12 rats subdivided equally into two subgroups IIA (subjected to clobetasol propionate cream) and IIB (subsequently exposed to skin abrasion). Group III (curcumin-treated Group) of 12 rats were subdivided equally into two subgroups IIIA and IIIB. Group IV (Aftamed-treated group) of 12 rats subdivided equally into two subgroups IVA and IVB. Skin biopsies were taken from the dorsum of rats 12th days from the stoppage of clobetasol propionate application. Sections were stained with hematoxylin and eosin, Masson's trichrome and immunohistochemichal stain for PCNA and CK19. Epidermal thicknesses, mean area percent of collagen fibers and mean number of PCNA and CK19 immunopositive cells were measured. Steroid-exposed group showed thinning of epidermal and dermal layers with marked decrease in numbers of hair follicles and sebaceous glands with delay in wound healing. Increased epidermal thickness and reorganized dermal structural elements with increased PCNA and CK19 immunopositive cells are more obvious in curcumin than aftamed treated group. These findings suggest that topical application of curcumin had more improving effect on skin and its abrasions rather than aftamed gel |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Skin atrophy |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Topical steroids |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Wound |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mohamed Deiaa Eldin Mohamed Elshafie , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Nagwa Abdelwahab Ahmed , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Sohair Ahmed Fawzy Tawfiq , |
Relator term | |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Samia |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.16.Ph.D.2018.Sa.H | 01010110075481000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.16.Ph.D.2018.Sa.H | 01020110075481000 | 22.09.2023 | CD - Rom | 75481.CD |