Study of the possible neuroprotective effect of stem cells on an experimentally induced model for multiple sclerosis in experimental animals / (Record no. 67003)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03126cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032029.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180809s2018 ua dh f m 000 0 eng |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.Ph.D.2018.Ma.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marwa Mohamed Mahfouz |
| 245 10 - TITLE STATEMENT | |
| Title | Study of the possible neuroprotective effect of stem cells on an experimentally induced model for multiple sclerosis in experimental animals / |
| Statement of responsibility, etc. | Marwa Mohamed Mahfouz ; Supervised Sanaa A. Kenawy , Hanaa A. Mansour , Rania M. Abdelsalam |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | درا{uئإآ٣}{uئإ٩٤} ا{uئإؤئ}{uئإ٩٨}{uئإ٨٤}{uئإ٩آ}{uئآئئ}{uئإءإ} ا{uئإؤئ}{uئإإإ}ا{uئإؤ٧}{uئإئ٠} ا{uئإؤئ}{uئإإ٤}{uئإء٤}{uئإ٩٨}{uئإإ٤}{uئإؤإ} {uئإؤئ}{uئإإ٠}{uئإء٨}{uئإئأ}{uئآئإ}{uئإ٨إ} ا{uئإؤئ}{uئإء٠}{uئإءأ}{uئإأآ}{uئآئئ}{uئإ٩٤} {uئإؤ٣}{uئإئ٠} {uئإإ٧}{uئإإ٤}{uئإإإ}ذج ا{uئإآ٣}{uئإ٩٨}{uئإء٤}{uئإءء}اث {uئإؤئ}{uئإإ٠}{uئإ٩٨}{uئإآأ}{uئإإ٠}{uئإ٩٠} ا{uئإؤئ}{uئإإ٤}{uئإ٩٨}{uئإأأ}{uئإءء}د {uئإؤ٣}{uئإئ٠} {uئإء٣}{uئآئئ}{uئإإإ}ا{uئإإ٧}{uئإ٨إ}ت ا{uئإؤئ}{uئإ٩٨}{uئإء٠}{uئإ٨إ}رب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marwa Mohamed Mahfouz , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 176 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Multiple sclerosis (MS) is a chronic autoimmune demyelinating neurodegenerative central nervous system disorder. The aim of the present study was to investigate the prophylactic effect exerted by the one-time intraperitoneal injection of mesenchymal stem cells (MSCs) 1{u00D7}106 and 14-day intraperitoneal injection of methylprednisolone (MP) 40 mg/kg in an experimental autoimmune encephalomyelitis (EAE) model. EAE was induced by intradermal injection of rat spinal cord homogenate with complete Freund{u2019}s adjuvant in Swiss mice. Results of MSCs and MP-treated mice showed a significantly milder disease and fewer clinical scores compared to control mice. They suppressed tumor necrosis factor-alpha and myeloperoxidase and increased interleukin 10, whereas thiobarbituric acid reactive substances and nitric oxide brain contents were reduced to comparable levels between treatment groups. Brain content of GSH was significantly higher in MSCs-treated mice than control mice. It is evident that MSCs have relevant prophylactic effect in an animal model of MS and might represent a valuable tool for stem cell based therapy in MS |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Encephalomyelitis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Methylprednisolone |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mice |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanaa A. Mansour , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania M. Abdel Salam , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanaa A. Kenawy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.Ph.D.2018.Ma.S | 01010110075499000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.Ph.D.2018.Ma.S | 01020110075499000 | 22.09.2023 | CD - Rom | 75499.CD |