An immunohistochemical comparison between CD105 and CD31 microvessel density for better evaluation of angiogenesis in oral epithelial dysplasia and oral squamous cell carcinoma / (Record no. 67109)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03120cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032033.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180816s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.14.Ph.D.2017.Am.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amina Fouad Abdelhamid Farag |
| 245 13 - TITLE STATEMENT | |
| Title | An immunohistochemical comparison between CD105 and CD31 microvessel density for better evaluation of angiogenesis in oral epithelial dysplasia and oral squamous cell carcinoma / |
| Statement of responsibility, etc. | Amina Fouad Abdelhamid Farag ; Supervised Mohsen Kazem Abdellatif , Nahed Emad Eldeen Aboazma , Rhab Fawzi Kasem |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | في كثافة الأوعية الدموية لتقييم الأفضل لعملية تكوين الأوعية الدموية الجديدة فى عسر التنشوء الظهارى و سرطان الخلايا الحرشفية بالفم CD31و CD105مقارنة نسيجية كيميائية مناعية بين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Amina Fouad Abdelhamid Farag , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 153 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The tumor-induced angiogenesis is used as a reliable marker for tumor progression and metastasis. CD105 has been suggested as a marker with a greater specificity for tumor-induced angiogenesis since it is strongly up-regulated on proliferating endothelial cells of newly formed blood vessels while it shows no or only weak expression in normal pre-existing ones unlike CD31 which can not differentiate the newly formed tumoral vessels from normal pre-existing ones. This study was designed to measure the microvessel density (MVD) in oral epithelial dysplasia and oral squamous cell carcinoma using CD105 and CD31. A total of 40 oral epithelial dysplasia and oral squamous cell carcinoma specimens were immunostained with CD105 and CD31. Then MVD was measured according to 2hot spot method3 in 3 high power microscopic fields at a magnification x200. The number of immunostained blood vessels increased from normal through dysplasia to carcinoma with a mean value of 1.5±0.5, 3.2±1 and 5.263±0.8 for CD105 and 3.6±1.02, 7.6±0.8 and 9.77±1.75 for CD31 respectively. CD31 showed positive immunoreaction in all blood vessels while CD105 revealed positive immunoreactivity only in the newly formed blood vessels while the native ones showed weak to negative immunoexpressions. Conclusion: CD105 can be considered as a more specific marker for measuring the tumor-induced angiogenesis compared to the commonly used panendothelial marker CD31 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Angiogenesis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CD105 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | CD31 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohsen Kazem Abdellatif , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nahed Emad Eldeen Aboazma , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rhab Fawzi Kasem , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.14.Ph.D.2017.Am.I | 01010110075548000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.14.Ph.D.2017.Am.I | 01020110075548000 | 22.09.2023 | CD - Rom | 75548.CD |