Possible renal protective effect of thiamine & ACEI in modulating the course of nephrogenic complications in type II diabetic rats / (Record no. 67192)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03325cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032035.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180829s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.30.M.Sc.2017.Mi.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mina Joseph Aiad |
| 245 10 - TITLE STATEMENT | |
| Title | Possible renal protective effect of thiamine & ACEI in modulating the course of nephrogenic complications in type II diabetic rats / |
| Statement of responsibility, etc. | Mina Joseph Aiad ; Supervised Akef Abdelhalim Khowailed , Hanan Hassan Fouad , Mohamed Mansour Khalifa |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التأثير الوقائى المحتمل للثيامين ومثبط الإنزيم المحول للأنجيوتنسين فى تعديل المسار المرضى للمضاعفات الخاصة بالكلى فى الجرذان المصابة بمرض السكرى من النوع الثانى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mina Joseph Aiad , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 119 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objectives: Test the possible renoprotective effects of angiotensin converting enzyme inhibitor and thiamine in type 2 diabetic kidneys . Methods: A total of 50 adult albino rats were used in this study weighing 150-200 grams. The animals were housed in wire mesh cages at room temperature, with normal light/dark cycle. They were fed the commercial rat chow diet and had free access to water. These rats were divided into the following groups: : Group 1 : Control group, Group 2 : Type 2 diabetic rats, Group 3 : Type 2 diabetic nephropathy rats, Group 4 : Lisinopril-treated type 2 diabetic nephropathy rats, Group 5 : Thiamine mononitrate-treated type 2 diabetic nephropathy rats. Blood samples were collected for measurement of fasting blood glucose, fasting blood insulin, blood urea and blood albumin creatinine ratio . Homeostasis model assessment of insulin resistance was calculated. Urine samples were collected for measurement of urinary albumin excretion. Systolic blood pressure and diastolic blood pressure were also measured . Nuclear factor kappa B gene expression was estimated . Results: Treatment with angiotensin converting enzyme inhibitor reduced fasting blood glucose, fasting blood insulin, blood urea, urinary albumin excretion, nuclear factor kappa B gene expression, systolic blood pressure and diastolic blood pressure. Treatment with thiamine mononitrate reduced fasting blood glucose, blood urea, urinary albumin excretion and systolic blood pressure. Conclusion: The use of angiotensin converting enzyme inhibitor and thiamine in the treatment of kidney disease with type 2 diabetes significantly offered renal protection and improved the diabetic condition and may postpone the onset of renal injury in a type 2 diabetic rats |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetes |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nuclear factor kappa B |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thiamine |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Akef Abdelhalim Khowailed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Hassan Fouad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Mansour Khalifa , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.30.M.Sc.2017.Mi.P | 01010110075611000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.30.M.Sc.2017.Mi.P | 01020110075611000 | 22.09.2023 | CD - Rom | 75611.CD |