Biochemical effect of some natural organic compounds on diethylnitrosamine induced toxicity in experimental rats / (Record no. 67487)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03016cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032044.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180917s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.M.Sc.2017.Ya.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Yara Mohamed Taha Taha |
| 245 10 - TITLE STATEMENT | |
| Title | Biochemical effect of some natural organic compounds on diethylnitrosamine induced toxicity in experimental rats / |
| Statement of responsibility, etc. | Yara Mohamed Taha Taha ; Supervised Bahia Yehia Riad , Mohamed Ali Eldesouky , Maha Hanafy Mahmoud |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التأثير الكيميائي الحيوي لبعض المركبات العضوية الطبيعية علي سُمية ثنائي إيثيل نيتروزامين في جرذان التجارب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Yara Mohamed Taha Taha , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 150 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study was designed to investigate the chemoprotective effect of rosemary extract (RE), green tea extract (GTE) and rosmarinic acid (RA) against diethylnitrosamine (DEN) initiated and ferric nitrilotriacetate (Fe-NTA) promoted oxidative stress, renal and hepatic toxicity in Wistar rats. The induction of toxicity was initiated with a single i.p. injection of DEN (160 mg/kg b.wt.). After eighteen days, the toxicity was promoted with a single i.p. injection of Fe-NTA at a dose level of 5 mg Fe/kg b.wt. This study included 40 Male rats that were grouped into five: Group I included healthy rats, group II of rats received DEN+Fe-NTA, group III received 200 mg/kg b.wt. of RE for 2 weeks followed by DEN+Fe-NTA, group IV received 1 g/kg b.wt. of GTE for 2 weeks followed by DEN+Fe-NTA and group V received 50 mg/kg b.wt. of RA for 2 weeks followed by DEN+Fe-NTA. RE, GTE, RA continued to be given orally to the animals till the end of the experiment. Results: The administration of Fe-NTA after DEN dose to albino rats resulted in acute toxicity which was characterized by a highly significant elevation of serum urea, creatinine, uric acid, ALT, AST, serum, renal and hepatic MDA and TNF-Ü (P=0.000) with vacuolation of epithelial lining renal tubules and necrosis of sporadic hepatocytes. The oral administration of RE, GTE and RA prior to DEN+Fe-NTA treatment could ameliorate the increased levels of the aforementioned parameters with GTE of the more pronounced effect on kidney and liver function parameters while RA showed the best antioxidant impact |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diethylnitrosamine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ferric nitrilotriacetate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Toxicity |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bahia Yehia Riad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Hanafy Mahmoud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Eldesouky , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.M.Sc.2017.Ya.B | 01010110075752000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.M.Sc.2017.Ya.B | 01020110075752000 | 22.09.2023 | CD - Rom | 75752.CD |