Synthesis of some new azines and their fused derivatives of expected biological activity / (Record no. 67496)
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000 -LEADER | |
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fixed length control field | 02758cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223032044.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 180917s2017 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.12.10.M.Sc.2017.Kh.S |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Khalid Gamal Salah Eldin Mohamed |
245 10 - TITLE STATEMENT | |
Title | Synthesis of some new azines and their fused derivatives of expected biological activity / |
Statement of responsibility, etc. | Khalid Gamal Salah Eldin Mohamed ; Supervised Nadia Hanafy Metwally , Mohamed Mohamed Mohamed Youssef , Rasha Abdelaziz Mohamed Faty |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | تشييد بعض الأزينات الجديدة ومشتقاتها الملتحمة ذات نشاط بيولوجي متوقع |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Khalid Gamal Salah Eldin Mohamed , |
Date of publication, distribution, etc. | 2017 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 124 P. : |
Other physical details | charts ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
520 ## - SUMMARY, ETC. | |
Summary, etc. | The condensation of 2-cyano-N-(6-methylpyridin-2-yl)acetamide (3) with various aromatic aldehydes afforded the corresponding arylidenes. On the other hand, compound 3 was treated with pentane-2,4-dione gave the corresponding 2-pyridinone derivative 10. Also, cyclocondensation of compound 3 with salicylaldehyde derivatives afforded 2-iminochromene derivatives 12a,b. Coupling of compounds 3 with aryldiazonium chlorides led to the formation of 2-arylhydrazono derivatives 15a-f. The reaction of compounds 3 with phenyl isothiocyanate, followed by addition of Ü-haloesters afforded thiazole derivatives. The 5-amino pyrazole derivative 21 reacted with some active methylene compounds such as acetyl acetone and ethyl acetoacetate to give pyrazolopyrimidines. Treatment of enaminone derivative 26 with hydrazine hydrate or phenylhydrazine yielded aminopyrazoles 28a,b, respectively. Refluxing of enaminone 26 with diaminopyrazoles afforded compounds 30a-e. Also, reaction of enaminone derivative with guindine nitrate afforded diaminopyrimidine derivative 32. The structure of all the newly synthesized compounds was elucidated by elemental analyses, spectral data and plausible mechanisms have been postulated to account for their formation.The anticancer activity of some new selected products was also investigated |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | 2-Cyano-N-(6-methylpyridin-2-yl)acetamide |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | 2-Imino-chromenes |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Pyridines |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mohamed Mohamed Mohamed Youssef , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Nadia Hanafy Metwally , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Rasha Abdelaziz Mohamed Faty , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Shimaa |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.10.M.Sc.2017.Kh.S | 01010110075755000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.10.M.Sc.2017.Kh.S | 01020110075755000 | 22.09.2023 | CD - Rom | 75755.CD |