Serum copeptin in the diagnosis of diabetes insipidus / (Record no. 67597)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03072cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180922s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2018.Ah.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Samir Abdalla Abdelaziz |
| 245 10 - TITLE STATEMENT | |
| Title | Serum copeptin in the diagnosis of diabetes insipidus / |
| Statement of responsibility, etc. | Ahmed Samir Abdalla Abdelaziz ; Supervised Ghada Mohammad Anwar , Sahar Abdelatty Sharaf , Noha Musa Azab |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | كوبيبتن بالدم لتشخيص مرض السكري الكاذب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Samir Abdalla Abdelaziz , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 101 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background/aim:There are 2 main types of diabetes inspidius (DI), central DI due to vasopressin deficiency and nephrogenic DI due to nephrons insensitivity to vasopressin. Water deprivation test is the cornerstone investigation in diagnosing and differentiating DI types. The aim of this study was to investigate the efficiency of serum copeptin (part of the vasopressin) in diagnosing and differentiating the types of DI. Materials and methods:Twenty fiveEgyptian children havingDI and 25 healthy control subjects were recruited fromspecialized children'shospital,CairoUniversity and Atfal Masr hospital.Full history and clinical examination were done.Weight, vital signs, 24 hour urine volume, baseline electrolytes, plasma and urine osmolalitywere assessed. Water deprivation tests results were obtained from patient's files. Serum copeptin was performed by ELISA technique. Results:There were significant difference between the DI patients and controls in serum creatinine and potassium (p values 0.036 and 0.003 respectively). While serum copeptin (pg/ml) showed insignificant difference between DI patient's and control subject (P value 0.71). The 25 DI patients were divided into: 19 with central DI and 6 with nephrogenic DI according to water deprivation test. Both groups showed insignificant difference in post dehydration osmolality (p value 0.17), whileboth groups showedsignificant difference in average urine output (ml/h) and average urine osmolality (mosm/l) after minirin intake with p values of 0.002 and 0.002 respectively.Serum BUN, creatinine and plasma osmolality levels were higher in nephrogenic DI withsignificant statistical difference (p values of 0.04, 0.02 and <.001respectively). However serum copeptinshowed insignificant difference between both groups. Conclusion:Serum copeptinmay have poor diagnostic value for diabetes insipidus |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Copeptin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetes insipidus |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Water deprivation |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghada Mohammad Anwar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noha Musa Azab , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sahar Abdelatty Sharaf , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2018.Ah.S | 01010110075883000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2018.Ah.S | 01020110075883000 | 22.09.2023 | CD - Rom | 75883.CD |