MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02289cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
180930s2018 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.08.M.Sc.2018.Di.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Diena Essam Aboelezz |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Development of gastroretentive sustained release drug delivery system for certain antibiotic and its in-vitro and in-vivo evaluation / |
| Statement of responsibility, etc. |
Diena Essam Aboelezz ; Supervised Ahmed Hassan Elhafeey , Yousry Mahmoud Elsayed , Ibrahim Hassan Elsayed |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
تطوير نظام توصيل محتجز معويا لإطالة مفعول مضاد حيوى وتقييمه معمليا وحيويا |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Diena Essam Aboelezz , |
| Date of publication, distribution, etc. |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
171 P. : |
| Other physical details |
charts ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Gastric retention is designed to prolong gastric residence time of oral controlled release dosage forms. Prolonged contact time of drug with the gastrointestinal mucosa, leads to higher bioavailability, and hence therapeutic efficacy, reduced time intervals for drug administration, potentially reduced dose size and thus improved patient compliance. It helps in sustaining drug delivery mainly for drugs that show site specific absorption from the stomach or the upper intestine. Ofloxacin is a broad-spectrum antimicrobial fluoroquinolone which has activity against a wide range of gram-negative and gram-positive microorganisms. It{u2019}s an off-white to pale yellow crystalline powder. Following oral administration, the bioavailability of ofloxacin in the tablet formulation is approximately 98%. Clearance of ofloxacin is reduced in patients with impaired renal function (creatinine clearance rate <50 mL/min), and dosage adjustment is necessary |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Gastroretentive |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Invitro and invivo evaluation |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Ofloxacin |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ahmed Hassan Elhafeey , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ibrahim Hassan Elsayed , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yousry Mahmoud Elsayed , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
