MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02576cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
181017s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.03.M.Sc.2018.Is.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Israa Mamdouh Nour |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Analysis of some drugs containing Amino group / |
| Statement of responsibility, etc. |
Israa Mamdouh Nour ; Supervised Mostafa Abdelaty Shehata , Mohamed Refaat Elghobashy , Nagiba Yehia Mohamed |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
تحليل لبعض الادويه التي تحتوي علي مجموعه الامينو |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Israa Mamdouh Nour , |
| Date of publication, distribution, etc. |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
156 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
This work is concerned with the quantitative determination of different drugs containing amino group namely, brinzolamide(BRZ), timolol(TML) and bumadiazone in their pure form, laboratory prepared mixtures and their pharmaceutical dosage forms in the presence of co-formulated excipients. In this study, different analytical techniques were developed, which include spectrophotometric, chemmometric and chromatographic methods for estimation of the drugs under study. Several experimental conditions were developed for optimization of the adopted methods.In part I; General introduction and literature review of brinzolamide (BRZ) and timolol (TML) were described. This part described also different analytical methods for the quantitative determination of BRZ and TML in their combination either in pure form or dosage form including spectrophotometry (ratio difference (RD), mean centering of ratio spectra (MCR), area under the curve (AUC) and Bivariate (BV)(, UV-Chemometry (PLS, PCR), TLC-Densitometry and HPLC. In part II; General introduction and literature review of bumadiazone (BDZ). Then different stability indicating methods were described for determination of bumadiazone in the presence of Its degradation product including spectrophotometric methods (ratio difference (RD), dual wave length, absorbance subtraction (AS) and absorbance ratio (AR)) and HPLC method |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Brinzolamide |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Bumadizone |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Timolol |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Refaat Elghobashy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mostafa Abdelaty Shehata , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nagiba Yehia Mohamed , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Enas |
| Reviser |
Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
