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Effects of mesenchymal stem cells on bone healing in rat bisphosphonate-Induced osteonecrotic teeth sockets : (Record no. 69398)

MARC details
000 -LEADER
fixed length control field 03091cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032143.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190103s2017 ua o f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.09.14.M.Sc.2017.Sa.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Samar Ali Hasan Altowity
245 10 - TITLE STATEMENT
Title Effects of mesenchymal stem cells on bone healing in rat bisphosphonate-Induced osteonecrotic teeth sockets :
Remainder of title An animal study /
Statement of responsibility, etc. Samar Ali Hasan Altowity ; Supervised Amal Hassan Abdelrahman , Rehab Fawzi Mahmoud , Mohammed Mahmoud Elsebaie
246 15 - VARYING FORM OF TITLE
Title proper/short title تاثير الخلايا الجذعيه الضامه على التئام العظم فى فجوات الخلع للفئران بعد استحداث تنخر العظم باستخدام مادة البايسفسفونيت
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Samar Ali Hasan Altowity ,
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 117 P. :
Other physical details photographs ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology
520 ## - SUMMARY, ETC.
Summary, etc. Aim: Evaluate the effect of MSCs on the healing (regenerative) potentials of the bone in bisphosphonate-induced osteonecrotic teeth socket. Material and methods: A total of twenty-four adult male rats with age ranging from 3 to 4 months and weight ranging from 190-250g were conducted on this study. BRONJ was generated by BPs (Zometa), dexamethozone and mandibular first molar extraction in all rats. After 3 weeks of BRONJ induction, rats were divided into two groups, each consisting 12 rats, the experimental group treated with MSCs topical application and the control group was left untreated. Also, each group was further subdivided into two groups 6 rats for each subgroup a according to sacrifice date at 2 weeks and 4 weeks intervals after MSCs application. The rats were sacrificed by overdose of anesthetic solution (1ml/100gm) according to the research animal guidelines of euthanasia. The mandible of all rats were dissected out and prepared for histopathological examination using (H and E stain), histochemical examination using (masson{u2019}s trichrome) and immunohistochemical analysis, using osteopontin antibody. Results: Revealed formation of new bone in osteonecrotic teeth sockets which are treated with MSCs while progression of BRONJ and no new bone formation in control group. A highly significant difference was detected between MSCs group and control group. Conclusion: MSCs topical treatment approach might help in restoring, maintaining or improving defective tissue functions that have been compromised by BRONJ
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Bisphosphonate
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Mesenchymal stem cells
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Osteonecrosis of the jaw
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Amal Hassan Abdelrahman ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohammed Mahmoud Elsebaie ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Rehab Fawzi Mahmoud ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Samia
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.09.14.M.Sc.2017.Sa.E 01010110076709000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.09.14.M.Sc.2017.Sa.E 01020110076709000 22.09.2023 CD - Rom 76709.CD