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Isolation and characterization of foot and mouth disease viruses from vaccinated cattle in Egypt year 2015-2016-2017 / (Record no. 69527)

MARC details
000 -LEADER
fixed length control field 03009cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190112s2018 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.10.17.M.Sc.2018.Di.I
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Dina Aly Abdulzaher
245 10 - TITLE STATEMENT
Title Isolation and characterization of foot and mouth disease viruses from vaccinated cattle in Egypt year 2015-2016-2017 /
Statement of responsibility, etc. Dina A. Abdulzaher ; Supervised Hussein Aly Hussein , Ayman Hani Eldeeb , Momtaz Abdelhady Shaheen
246 15 - VARYING FORM OF TITLE
Title proper/short title عزل و توصيف لفيروسات مرض الحمى القلاعية من الأبقار المحصنة في مصر أعوام 2015-2016-2017
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Dina Aly Abdulzaher ,
Date of publication, distribution, etc. 2018
300 ## - PHYSICAL DESCRIPTION
Extent 130 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology
520 ## - SUMMARY, ETC.
Summary, etc. Foot and mouth disease (FMD) is responsible for serious economic losses in Egypt. Although vaccination is practiced as the main control strategy, failure of vaccination has been reported in many cases. Selection of FMD antigenic variants under the immune pressure of partially immunized animals has been previously recorded. The current study aimed to isolate and characterize foot and mouth disease virus (FMDV) strains circulating in the Egyptian vaccinated animals. Serotype O, A and SAT2 FMDVs were detected in different Egyptian governorates during 2015, 2016 and 2017. We report here the successful isolation of 15 FMDVs of the three serotypes. Phylogenetic analysis based on VP1 gene placed all serotype O isolates with EA-3 prototypes. There was a variation in 15-17 amino acids between serotype O isolates of 2015 and (2016 & 2017). Serotype A isolates belonged to A-Iran-05 lineage with the exception of one isolate of 2016 which clustered with the African strains of G-IV. Serotype SAT2 FMDV was detected in two samples of 2017 and both were of lineage Alx-12 of topotype VII. Virus neutralization test (VNT) using serotype-specific sera confirmed the serotyping of the isolated viruses and determined the antigenic relatedness between the isolates and the currently used vaccine strains. A drop in the neutralizing antibody titer of some serotype O and A isolates could be attributed to mutation in critical amino acids in the neutralizing antigenic sites. Hence, this work suggests the significance of amino acids substitution within the virus antigenic sites in antibody neutralization and immune escape
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Foot and Mouth Disease
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Molecular epidemiology
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Phylogenetic analysis
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ayman Hani Eldeeb ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Hussein Aly Hussein ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Momtaz Abdelhady Shaheen ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.10.17.M.Sc.2018.Di.I 01010110076760000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.10.17.M.Sc.2018.Di.I 01020110076760000 22.09.2023 CD - Rom 76760.CD