Isolation and characterization of foot and mouth disease viruses from vaccinated cattle in Egypt year 2015-2016-2017 / (Record no. 69527)
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000 -LEADER | |
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fixed length control field | 03009cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 190112s2018 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.10.17.M.Sc.2018.Di.I |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Dina Aly Abdulzaher |
245 10 - TITLE STATEMENT | |
Title | Isolation and characterization of foot and mouth disease viruses from vaccinated cattle in Egypt year 2015-2016-2017 / |
Statement of responsibility, etc. | Dina A. Abdulzaher ; Supervised Hussein Aly Hussein , Ayman Hani Eldeeb , Momtaz Abdelhady Shaheen |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | عزل و توصيف لفيروسات مرض الحمى القلاعية من الأبقار المحصنة في مصر أعوام 2015-2016-2017 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Dina Aly Abdulzaher , |
Date of publication, distribution, etc. | 2018 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 130 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Foot and mouth disease (FMD) is responsible for serious economic losses in Egypt. Although vaccination is practiced as the main control strategy, failure of vaccination has been reported in many cases. Selection of FMD antigenic variants under the immune pressure of partially immunized animals has been previously recorded. The current study aimed to isolate and characterize foot and mouth disease virus (FMDV) strains circulating in the Egyptian vaccinated animals. Serotype O, A and SAT2 FMDVs were detected in different Egyptian governorates during 2015, 2016 and 2017. We report here the successful isolation of 15 FMDVs of the three serotypes. Phylogenetic analysis based on VP1 gene placed all serotype O isolates with EA-3 prototypes. There was a variation in 15-17 amino acids between serotype O isolates of 2015 and (2016 & 2017). Serotype A isolates belonged to A-Iran-05 lineage with the exception of one isolate of 2016 which clustered with the African strains of G-IV. Serotype SAT2 FMDV was detected in two samples of 2017 and both were of lineage Alx-12 of topotype VII. Virus neutralization test (VNT) using serotype-specific sera confirmed the serotyping of the isolated viruses and determined the antigenic relatedness between the isolates and the currently used vaccine strains. A drop in the neutralizing antibody titer of some serotype O and A isolates could be attributed to mutation in critical amino acids in the neutralizing antigenic sites. Hence, this work suggests the significance of amino acids substitution within the virus antigenic sites in antibody neutralization and immune escape |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Foot and Mouth Disease |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Molecular epidemiology |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Phylogenetic analysis |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Ayman Hani Eldeeb , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Hussein Aly Hussein , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Momtaz Abdelhady Shaheen , |
Relator term | |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Shimaa |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.17.M.Sc.2018.Di.I | 01010110076760000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.17.M.Sc.2018.Di.I | 01020110076760000 | 22.09.2023 | CD - Rom | 76760.CD |