Evaluation of the possible neurobehavioral effects of vinpocetine in parkinsonian-like models in rats / (Record no. 69762)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02821cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032154.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190127s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.Ph.D.2018.Ra.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rania Ibrahim Ahmed Nadeem |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the possible neurobehavioral effects of vinpocetine in parkinsonian-like models in rats / |
| Statement of responsibility, etc. | Rania Ibrahim Ahmed Nadeem ; Supervised Bahia Mohamed Elsayeh , Ezz Eldin Eldenshary , Hebatalla Ibrahim Ahmed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم التأثيرات السلوكية العصبية المحتملة للڨينبوستين فى نموذجين مشابهين لنموذج الشلل الرعاش فى الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Rania Ibrahim Ahmed Nadeem , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 195 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Parkinson{u2019}s disease (PD) is the second most common neurodegenerative disease. Clinical features include motor (bradykinesia, rigidity, resting tremor) and non-motor (depression, sleep disturbances, memory deficits) symptoms. It is characterized by progressive loss of dopaminergic neurons in the substantia nigra (SN) with subsequent reduction in striatal dopamine level. Current therapeutic strategies for PD focus mainly on reducing the severity of its symptoms using dopaminergic medications, while the progressive loss of neurons cannot be stopped or reverted by these medications. Manganese (Mn) is required for many essential biological processes as well as in the development and functioning of the brain. Excessive accumulation of Mn in the brain may cause serious central nervous system dysfunction known as manganism, a motor disorder associated with cognitive and neuropsychiatric deficits similar to parkinsonism. Vinpocetine a synthetic derivative of the alkaloid vincamine, is used to improve the cognitive function in cerebrovascular diseases. It possesses antioxidant and anti-inflammatory properties. The cognitive improvement properties and the antioxidant and anti-inflammatory effects of vinpocetine, make it a potential candidate for the treatment of neurodegenerative conditions, such as PD and Alzheimer{u2019}s disease |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Manganese |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Manganism |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Parkinson{u2019}s disease |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bahia Mohamed Elsayeh , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ezz Eldin Eldenshary , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hebatalla Ibrahim Ahmed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.Ph.D.2018.Ra.E | 01010110076985000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.Ph.D.2018.Ra.E | 01020110076985000 | 22.09.2023 | CD - Rom | 76985.CD |