Estimation of histone deacetylase 1 in patients with acne vulgaris and alopecia areata / (Record no. 70132)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02713cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190213s2018 ua h f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2018.Ma.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maha Samir Abdelsalam Elsayed |
| 245 10 - TITLE STATEMENT | |
| Title | Estimation of histone deacetylase 1 in patients with acne vulgaris and alopecia areata / |
| Statement of responsibility, etc. | Maha Samir Abdelsalam Elsayed ; Supervised Iman Muhammad Amin , Marwa Ahmed Ezzat , Laila Ahmad Rashed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقدير هيستون دي أسيتيليز1 في المرضي الذين يعانون من حب الشباب و داء الثعلبة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Maha Samir Abdelsalam Elsayed , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 91 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University -Faculty of Medicine - Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Rationale and background: Histone deacetylases (HDAC) are a class of enzymes that allow the histones to wrap the DNA more tightly with the concomitant suppression of gene transcription. HDACs are present in the epidermal layer of the skin, hairs (outer root sheath, and hair matrix), scales, claws and glands. In alopecia areata (AA), Epigenetic factors are involved. The expression of histone deacetylase 1 (HDAC1) was significantly increased with decreased expression of HDAC2 and HDAC7 in peripheral blood mononuclear cells (PBMCs) of patients with AA. These findings prove the involvement of epigenetic factors in the development of the disease. Acne vulgaris has a multifactorial pathogenesis, of which the key factor is genetics. Epigenetic factors have important role in its pathogenesis. Objective: The current study aimed to estimate the serum level of histone deacetylase 1 (HDAC1) in patients with alopecia areata (AA) and acne vulgaris and try to elucidate its possible role in the aetiopathogenesis of both diseases.Patients and methods: This case control study was carried out on 25 alopecia areata patients,26 acne patients & 25 healthy controls. Informed written consents were obtained from all the participants. Patients were subjected to personal history and clinical examination. Photos were taken from patients. Blood samples were collected from the participants to measure the level of HDAC1 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acne vulgaris |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Alopecia areata |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | HDAC1 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Muhammad Amin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laila Ahmad Rashed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Ezzat , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2018.Ma.E | 01010110077143000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2018.Ma.E | 01020110077143000 | 22.09.2023 | CD - Rom | 77143.CD |