MARC details
| 000 -LEADER |
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| fixed length control field |
03041cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190219s2018 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.08.03.M.Sc.2018.Em.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Eman Mohamed Morgan |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Analytical study of some drugs containing carboxylic acid derivatives / |
| Statement of responsibility, etc. |
Eman Mohamed Morgan ; Supervised Mohamed Abdelkawy , Hayam Mahmoud Lotfy , Yasmin Mohamed Fayez |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة تحليلية على بعض العقاقير التى تحتوى على مشتقات مجموعة الكاربوكسيل |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Eman Mohamed Morgan , |
| Date of publication, distribution, etc. |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
241 P. : |
| Other physical details |
charts ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
This thesis is concerned with the quantitative determination of some drugs containing carboxylic acid derivatives; namely Valaciclovir Hydrochloride and Trimebutine Maleate in their pure powdered form, in presence of their degradation products and application on pharmaceutical formulations. In this thesis; different analytical techniques were adopted, namely, UV-spectrophotometric, visible spectrophotometric, chromatographic and electrochemical methods for the determination of the previously mentioned compounds in their pure powder, laboratory prepared mixtures and pharmaceutical formulations. In part I; General introduction and literature review of valaciclovir hydrochloride (VAL) and its active metabolite aciclovir (ACI) were described. This part described also the quantitative determination of VAL in pure form or dosage form using UV-spectrophotometry including six methods namely, dual wavelength (DW), induced dual wavelength (IDW), ratio difference (RD), constant center coupled with spectrum subtraction spectrophotometric method (CC-SS), the first derivative of the ratio spectra (DD1) and mean centering of ratio spectra (MCR), visible-spectrophotometric method, chromatographic (RP-UPLC method and TLC-densitometry) methods and electrochemical method (ISE). In part II; General introduction and literature review of trimebutine maleate (TM) were described. Then different analytical methods were described for the determination of the studied drugs in their pure form or dosage form including four spectrophotometric methods namely, dual wavelength (DW), second derivative (D2), ratio difference (RD) and constant center coupled with spectrum subtraction spectrophotometric method (CC-SS) and chromatographic (RP-HPLC and TLC-densitometry) methods |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Trimebutine maleate |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
UV-spectrophotometric methods |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Valaciclovir hydrochloride |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hayam Mahmoud Lotfy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Abdelkawy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yasmin Mohamed Fayez , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
