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Evaluation of the protective effects of N-acetylcysteine against malathion-induced toxicity in albino rats / (Record no. 71447)

MARC details
000 -LEADER
fixed length control field 02623cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190414s2018 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.13.Ph.D.2018.He.E
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Heba Mohammed Aboubakr
245 10 - TITLE STATEMENT
Title Evaluation of the protective effects of N-acetylcysteine against malathion-induced toxicity in albino rats /
Statement of responsibility, etc. Heba Mohammed Aboubakr ; Supervised Eman Abdelfattah Mohamed Elzohairy , Abla Abdelrahman Ali , Laila Ahmed Rashed
246 15 - VARYING FORM OF TITLE
Title proper/short title تقييم التأثيرات الوقائية ل ن-اسيتيل سيستيين على التسمم الناتج عن المالاثيون فى الفئران البيضاء
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Heba Mohammed Aboubakr ,
Date of publication, distribution, etc. 2018
300 ## - PHYSICAL DESCRIPTION
Extent 143 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Forensic Medicine Toxicology
520 ## - SUMMARY, ETC.
Summary, etc. Background: Malathion is a widely used organophosphorus insecticide, however, its unregulated use have produced severe environmental pollution and potential health hazards. N-acetylcysteine (NAC) is a known glutathione precursor and nowadays there is a growing interest concerning its beneficial effects against pesticides-induced toxicity. Objectives: The present study was designed to investigate malathion-induced hepatotoxicity in the form of liver cell injury and histopathological changes in liver tissue, immunotoxicity and genotoxicity and also to clarify the possible causing mechanisms of these hazards and finally, to evaluate the protective effects of NAC against these hazards in rats that were exposed to low dose malathion for 90 consecutive days. Materials and Methods: 100 adult male albino rats were randomly divided into four groups comprised of 25 rats each. For 90 consecutive days, Group 1 received distilled water daily, Group 2 received NAC in a dose of 150 mg kg/day, Group 3 received malathion in a dose of 50 mg/kg/day and Group 4 received malathion in a dose of 50 mg/kg/day followed by NAC in a dose of 150 mg kg/day. On the 90{u036D} {u036A} day, samples were collected for biochemical and histopathological analysis
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Hepatotoxicity
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term immunotoxicity
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Malathion
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Abla Abdelrahman Ali ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Eman Abdelfattah Mohamed Elzohairy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Laila Ahmed Rashed ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Samia
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.13.Ph.D.2018.He.E 01010110077690000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.13.Ph.D.2018.He.E 01020110077690000 22.09.2023 CD - Rom 77690.CD