Synthesis of some new heterocyclic compounds with expected biological activity from cyanoacetamide derivatives / (Record no. 71569)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02835cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032248.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190420s2018 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.10.M.Sc.2018.Zi.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Zinab Atwa Saad Atwa Elnaggar |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis of some new heterocyclic compounds with expected biological activity from cyanoacetamide derivatives / |
| Statement of responsibility, etc. | Zinab Atwa Saad Atwa Elnaggar ; Supervised Hussein Fouad Zohdi , Ibrahim Adel Ibrahim Eldosoky |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تشييد بعض المركبات الغير متجانسة الحلقة الجديدة و المتوقع لها نشاط بيولوجى من مشتقات سيانو أسيتاميد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Zinab Atwa Saad Atwa Elnaggar , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 113 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The original work of this thesis includes: A series of arylidene derivatives 4a-l, 2-imino-chromene derivatives 6a-e and aryl hydrazones derivates 8a-d were synthesized via the reaction of 2-cyano-N-(1,3-dihydroxy-2-(hydroxylmethyl) propan-2-yl) acetamide 2 with aldehydes and aryldiazonium salts. Refluxing cyanoacetamide derivative 2 with phenyl isothiocyanate and elemental sulfur afforded 4-amino-N-(1,3-dihydroxy-2-(hydroxymethyl) propan-2-yl)-3-phenyl-2- thioxo-2, 3-5-carboxamide 9. Also, reaction of 2 with cyclopentanone or cyclohexanone and elemental sulfur gave the corresponding aminothiophene derivatives 10. Treatment of cyanoacetamide derivative 2 with pentane-2,4-dione provided aminothiophene derivative 11. Condensation of enaminonitrile derivative 12 with 4-(phenyldiazenyl)-1H- pyrazole-3, 5-diamine derivatives 13a-e furnished pyrazolo [1,5-a] pyrimidine derivatives 14a-e. Refluxing of 12 with cyanoguanidine and guanidine nitrate produced 2,4-diimino-1,2,3,4-tetrahydropyrimidine-5-carboxamides 15 and 16 respectivly. Also, grinding enaminonitrile 12 with hydrazine hydrate provided 3-amino-N-(1,3-dihydroxy-2-(hydroxymethyl) propan-2-yl)-1H-pyrazole-4-carboxamide 17. The newly synthesized compounds were proved by elemental and spectral data. All plausible mechanisms for their formation were discussed. Some of the selected products were tested and evaluated as antimicrobial agents |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 2-cyano-N-(1,3-dihydroxy-2-(hydroxy methyl) propan-2-yl)acetamide |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 2-imino-chromenes |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Arylidenes |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hussein Fouad Zohdi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ibrahim Adel Ibrahim Eldosoky , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.10.M.Sc.2018.Zi.S | 01010110077735000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.10.M.Sc.2018.Zi.S | 01020110077735000 | 22.09.2023 | CD - Rom | 77735.CD |