MARC details
000 -LEADER |
fixed length control field |
03093cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
190421s2018 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.31.Ph.D.2018.Ma.A |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Mai Ashraf Saad Zaghloul Mohamed |
245 10 - TITLE STATEMENT |
Title |
Added value of diffusion weighted magnetic resonance imaging (DWI MRI) in assessing the therapeutic response of neoadjuvant chemotherapy / radiotherapy (CRT) in advanced colo-rectal cancer / |
Statement of responsibility, etc. |
Mai Ashraf Saad Zaghloul Mohamed ; Supervised Lamiaa Ibrahim Abdelrahman Metwally , Mohamed Samy Elazab , Osman Mohamed Mansour |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
في تقييم استجابة سرطان القولون و المستقيم للعلاج الكيميائي و الإشعاعي (DWI MRI) دور أشعة الرنين المغناطيسي بالانْتِشار |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Mai Ashraf Saad Zaghloul Mohamed , |
Date of publication, distribution, etc. |
2018 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
202 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Fifty patients who met the inclusion and exclusion criteria were enrolled in this prospective study, from those attending the gastroenterology clinic of the surgical department of the National Cancer Institute during the period from January 2016 till January 2018, 30 female and 20 male patients, with mean age 49.4 years ± 15.28; age ranging from (22-79 years) were pathologically proven, received neoadjuvant CRT course of 6 weeks and were assessed by T2 WI & DW-MRI pre and post-CRT.All Images were independently reviewed by two readers blinded to the results to determine the detectability of rectal cancer, and the post therapeutic response.Results:Regarding the T staging; the majority of the cases 37(74 %) were initially diagnosed as T3 stage, 8(16%) as T4 stage and 5(10%) as T2 stage, while post-CRT findings were 31(62%) T3, 10(20%) T2, 9(18%) T4. T-stage down-staging of the 5 cases from T3 to T2 is seen post- CRT with a highly significant difference P-value < 0.005 (Z= -5.536). However only one case was found to progress from T3 to T4 stage.The mean tumor size pre-CRT was 7.66 cm ± 2.76 and decreased to 6.7 cm ± 2.82 post-CRT. The decrease in size post-CRT is highly significant with a P-value =0.000 (t-value= 4.477).Regarding the pathological subtypes 38 out of 50 cases (76%) were adenocarcinoma (mostly grade 2), 8 cases (16%) mucinous adenocarcinoma, 3 cases (6%) signet ring adenocarcinoma and 1 case (2%) was gastrointestinal-stromal tumor (GIST |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Assessing the therapeutic response |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Diffusion weighted magnetic resonance imaging (DWI MRI) |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Neoadjuvant chemotherapy / radiotherapy (CRT) |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Lamiaa Ibrahim Abdel Rahman Metwally , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohamed Samy Elazab , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Osman Mohamed Mansour , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Enas |
Reviser |
Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |