The wound healing potential of human exfoliated deciduous teeth (SHED) versus bone marrow derived mesenchymal stem cells (BM-MSC) in treating induced tongue ulcers in albino rats : (Record no. 71673)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03357cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032251.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190424s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.11.M.Sc.2018.Di.W |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dina Kamal Ahmed Mohamed |
| 245 14 - TITLE STATEMENT | |
| Title | The wound healing potential of human exfoliated deciduous teeth (SHED) versus bone marrow derived mesenchymal stem cells (BM-MSC) in treating induced tongue ulcers in albino rats : |
| Remainder of title | An animal study / |
| Statement of responsibility, etc. | Dina Kamal Ahmed Mohamed ; Supervised Samah Mehanni , Dalia Elbaz , Laila Ahmed Rashed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | إمكانيات الشفاء للخلايا الجذعية المشتقه من الأسنان اللبنية للإنسان مقابل المشتقة من نخاع العظم الوسيطة في علاج قرحة اللسان المستحثة في الفئران البيضاء : |
| Remainder of title | دراسة في الحيوانات |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Dina Kamal Ahmed Mohamed , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 135 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Surgery |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study was preformed to compare the healing potential of bone marrow derived stem cells (BM-MSCs) versus stem cells derived from human exfoliated teeth (SHED) in treating induced tongue ulcers in a rat animal model. Stem cells may act directly through differentiating into host cells or indirectly through secretion of growth factors and cytokines.The data were based on histopathological and histochemical examination, qRT-PCR gene detection for TGF-Ý1 and histomorphometric analysis. The experiment was conducted on 45 male albino rats. Rats were anesthetized, then tongue ulcers were induced by applying electrocautery pen tip.Two days were left for ulcer establishment. In the 3rd day the rats were randomly distributed into 3 equal groups. The first one was considered as control while the others were considered as experimental groups. The overall results of the present study demonstrated that both BM-MSC and SHED were effective in treatment of induced tongue ulcers. Both showed better healing than the control group. BM-MSCs showed superiority regarding the healed epithelial thickness, amount of mature collagen in early phases of healing and in amount of regenerating muscle fibers. SHED showed more adipocytes and increased innervation; both affect fibroblastic differentiation. Although BM-MSC may be superior to SHED. SHED can be obtained without any invasive procedure. They are obtained from shed deciduous teeth that are considered as a medical waste. TGF-Ý1 level increased by time in all groups. Its higher expression in both BM-MSCs and SHED groups in the early phases of wound healing accelerated wound healing process while its high expression later in the control group results in fibrosis |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Stem cells |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Tongue |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Wound healing |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalia Elbaz , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laila Ahmed Rashed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samah Mehanni , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.11.M.Sc.2018.Di.W | 01010110077936000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.11.M.Sc.2018.Di.W | 01020110077936000 | 22.09.2023 | CD - Rom | 77936.CD |