MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03097cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190502s2018 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.33.Ph.D.2018.Mo.F |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Abdallah Abdelaziz Abdallah |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Follow up of HCV reinfection, liver fibrosis progression and nutritional assessment in treated HCV/HIV Co-infected patients / |
| Statement of responsibility, etc. |
Mohamed Abdallah Abdelaziz Abdallah ; Supervised Hasan Ahmed Ali Elgarem , Neveen Helmy AboulSoud , Mohamed Ahmed Mohey Eldin |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
متابعة مرضى فيروس (سى) المصاحب لفيروس نقص المناعة البشرية فيما يتعلق بتطور التليف: إعادة الاصابه بالعدوى و التقييم الغذائى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Mohamed Abdallah Abdelaziz Abdallah , |
| Date of publication, distribution, etc. |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
130 P. ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background: Due to similarities in their mode of transmission; a large group of HIV/HCV has been discovered. An estimated 4{u2013}5 million people are infected with both HIV and HCV worldwide. Combined infection accelerates disease progression in addition to large numbers of HCV relapse after treatment. Treatment decision is always complicated due to poor immune state and drug-drug interactions with anti-retroviral therapy. Aim: We aim to assess the sustained virologic response, Re-infection, Liver fibrosis progression in combined HCV/HIV patients who are treated for HCV with special emphasis on their nutritional needs. Patient and methods: Fifty eligible patients with confirmed genotype 4 HCV/HIV co-infection were enrolled. They received HCV treatment (12 weeks of 400 mg of sofosbuvir daily plus daclatasvir 60 mg daily with dose adjustment for concomitant antiretroviral medications). Assessment of virologic response, re-infection, Liver fibrosis, biochemical changes were done up to 24 weeks after treatment. Results: Mean age of study participants was 34.68±10.38 years, 70% were on anti-retroviral therapy. Sustained virologic response at SVR24 was 93.48%. Hepatitis C eradication cause a significant improvement in liver transaminases (P Value: <0.001) and platelet count (P Value: 0.001). Significant liver fibrosis regression was noticed at SVR24 (P Value: 0.0008). Mean CD4 level were significantly improved (P Value: 0.0652). Conclusion: Treatment of HCV using Sofosbuvir / Daclatasvir regimen is highly effective, with a good safety profile. HCV eradication aids in liver fibrosis regression and normalization of liver transaminases |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
HCV |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
HCV/HIV Co-infected patients |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
HIV |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hasan Ahmed Ali Elgarem , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Ahmed Mohey Eldin , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Neveen Helmy AboulSoud , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
