MicroRNA let-7a-1, let-7d and let-7f gene expression in hepatocellular carcinoma patients / (Record no. 71898)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02568cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032258.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190509s2018 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.Ph.D.2018.Do.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mamdouh Aly Ahmad Abubakr |
| 245 10 - TITLE STATEMENT | |
| Title | MicroRNA let-7a-1, let-7d and let-7f gene expression in hepatocellular carcinoma patients / |
| Statement of responsibility, etc. | Doaa Mamdouh Aly Ahmad Abu-Bakr ; Supervised Nadida Abdulhameed Gohar , Afaf Ahmed Abdelhady , Mona Mohsen Abdulsalam |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فى مرضى سرطان الكبد let-7fو let-7d و let-7a-1 التعبير الجينى الخاص بالأحماض الريبونيوكليك الدقيقة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Doaa Mamdouh Aly Ahmad Abubakr , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 228 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Hepatocellular carcinoma is one of the most common and lethal malignant tumors worldwide. MicroRNAs are involved in the epigenetic mechanism{u2019}s implicated in HCC molecular pathogenesis. Measuring the levels of the circulating miRNAs to be used as biomarkers for malignancies has recently been investigated in the hope of identifying unique miRNA signatures in human tumors. Two clusters of microRNAs have been selected in this study; Let7-a-1, let-7d-1, let-7f-1 cluster and miR143/145 cluster. Aim of the study: To identify miRNA let-7 a-1, d-1, f-1 cluster and miRNA143/ 145 cluster gene expressions in HCC patients. Methods: The study included 40 Hepatocellular carcinoma patients, 40 chronic HCV patients divided into 2 subgroups, 20 patients with liver cirrhosis and 20 patients without liver cirrhosis, and 40 apparently healthy subjects as a control group. They were subjected to routine laboratory investigations and gene expression analysis for miRNA let-7 a-1, d-1, f-1 cluster and miRNA 143/ 145 cluster using quantitative SYBR Green reverse-transcription Real-Time polymerase chain reaction |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatocellular carcinoma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Let-7d-1 miRNA |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MicroRNA - Let-7a-1 miRNA |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Afaf Ahmed Abdelhady , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Mohsen Abdulsalam , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nadida Abdulhameed Gohar , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.Ph.D.2018.Do.M | 01010110077884000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.Ph.D.2018.Do.M | 01020110077884000 | 22.09.2023 | CD - Rom | 77884.CD |