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Assessment of cytokeratin 19 and its soluble salivary fragment cyfra 21-1 in benzanthracene induced dysplasia and tongue squamous cell carcinoma in rats : (Record no. 71931)

MARC details
000 -LEADER
fixed length control field 03004cam a2200313 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190512s2017 ua do f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.09.14.M.Sc.2017.Ha.A
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Hala Khaled Elsayed Mostafa
245 10 - TITLE STATEMENT
Title Assessment of cytokeratin 19 and its soluble salivary fragment cyfra 21-1 in benzanthracene induced dysplasia and tongue squamous cell carcinoma in rats :
Remainder of title An Animal Study /
Statement of responsibility, etc. Hala Khaled Elsayed Mostafa ; Supervised Amal Hassan Abdelrahman , Dina Soliman Khater
246 15 - VARYING FORM OF TITLE
Title proper/short title تقييم تواجد سى كى 19 و أجزائه الذائبه في العاب سيفرا21-1 في خلل تنسج الخاليا الفموية و سرطان اللسان الطالئي المستحدث في فئران التجارب:
Remainder of title دراسه حيوانيه
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Hala Khaled Elsayed Mostafa ,
Date of publication, distribution, etc. 2017
300 ## - PHYSICAL DESCRIPTION
Extent 101 P. :
Other physical details charts , photographs ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology
520 ## - SUMMARY, ETC.
Summary, etc. Head and neck cancer among the most common incident cancers in men worldwide. Early detection is the key to higher survival rate against this type of cancer. Cytokeratins are essential intracellular components, reflecting distinct cellular properties and differentiation stages in epithelial tissues. The CYFRA 21-1 assay, which is the soluble fragment of cytokeratin 19, has been proven capable of early .detection of epithelial carcinomas This study was conducted to correlate the immunoexpression of CK 19 with the concentration of its salivary fragments (CYFRA 21-1) for early detection of induced .dysplastic changes prior to malignant transformation in experimental rat The study was conducted on fourty four male albino rats with age ranging from 3 to 4 months and with a mean weight of 220 gm. They were divided into two groups, each consisting of 22 rats, the first group represents the control group I and the second group represents induced group II. Each group was subdivided into 5 subgroups A, B, C, D and E according to the time of euthanization with intervals of 9,12,15,18 and 21 weeks from time of induction respectively. In induced group II, the tongue mucosae of each rat were painted (topically) with dimethylbenz-anthracene and formaldehyde, .whereas group I served as positive control The Rats were euthanized according to the Research Animal Guidelines of Euthanasia (2013). The dissected tongue mucosae of rats were processed routinely to obtain 5 microns thick sections
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Head and neck cancer
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Cell Carcinoma
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Soluble Salivary
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Amal Hassan Abdelrahman ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Dina Soliman Khater ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Rania
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.09.14.M.Sc.2017.Ha.A 01010110078057000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.09.14.M.Sc.2017.Ha.A 01020110078057000 22.09.2023 CD - Rom 78057.CD