Assessment of cytokeratin 19 and its soluble salivary fragment cyfra 21-1 in benzanthracene induced dysplasia and tongue squamous cell carcinoma in rats : (Record no. 71931)
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000 -LEADER | |
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fixed length control field | 03004cam a2200313 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 190512s2017 ua do f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.09.14.M.Sc.2017.Ha.A |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Hala Khaled Elsayed Mostafa |
245 10 - TITLE STATEMENT | |
Title | Assessment of cytokeratin 19 and its soluble salivary fragment cyfra 21-1 in benzanthracene induced dysplasia and tongue squamous cell carcinoma in rats : |
Remainder of title | An Animal Study / |
Statement of responsibility, etc. | Hala Khaled Elsayed Mostafa ; Supervised Amal Hassan Abdelrahman , Dina Soliman Khater |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | تقييم تواجد سى كى 19 و أجزائه الذائبه في العاب سيفرا21-1 في خلل تنسج الخاليا الفموية و سرطان اللسان الطالئي المستحدث في فئران التجارب: |
Remainder of title | دراسه حيوانيه |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Hala Khaled Elsayed Mostafa , |
Date of publication, distribution, etc. | 2017 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 101 P. : |
Other physical details | charts , photographs ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Head and neck cancer among the most common incident cancers in men worldwide. Early detection is the key to higher survival rate against this type of cancer. Cytokeratins are essential intracellular components, reflecting distinct cellular properties and differentiation stages in epithelial tissues. The CYFRA 21-1 assay, which is the soluble fragment of cytokeratin 19, has been proven capable of early .detection of epithelial carcinomas This study was conducted to correlate the immunoexpression of CK 19 with the concentration of its salivary fragments (CYFRA 21-1) for early detection of induced .dysplastic changes prior to malignant transformation in experimental rat The study was conducted on fourty four male albino rats with age ranging from 3 to 4 months and with a mean weight of 220 gm. They were divided into two groups, each consisting of 22 rats, the first group represents the control group I and the second group represents induced group II. Each group was subdivided into 5 subgroups A, B, C, D and E according to the time of euthanization with intervals of 9,12,15,18 and 21 weeks from time of induction respectively. In induced group II, the tongue mucosae of each rat were painted (topically) with dimethylbenz-anthracene and formaldehyde, .whereas group I served as positive control The Rats were euthanized according to the Research Animal Guidelines of Euthanasia (2013). The dissected tongue mucosae of rats were processed routinely to obtain 5 microns thick sections |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 ## - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Head and neck cancer |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Cell Carcinoma |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Soluble Salivary |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Amal Hassan Abdelrahman , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Dina Soliman Khater , |
Relator term | |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Rania |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.14.M.Sc.2017.Ha.A | 01010110078057000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.14.M.Sc.2017.Ha.A | 01020110078057000 | 22.09.2023 | CD - Rom | 78057.CD |