Effect of antioxidants on behavioural, biochemical and histopathological modifications - neuroinflammation, neurodegeneration in alzheimer's disease rat model / (Record no. 72146)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02840cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190523s2018 ua o f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.02.Ph.D.2018.Em.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Hany Hassan Abdelnaby |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of antioxidants on behavioural, biochemical and histopathological modifications - neuroinflammation, neurodegeneration in alzheimer's disease rat model / |
| Statement of responsibility, etc. | Eman Hany Hassan Abdelnaby ; Supervised Mervat Mahmoud Kamel , Heba Said Ellethey , Kassem Gabr Aliraqi |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير مضادات الأكسدة على التغيرات السلوكية و البيوكيميائية و الهيستوباثولوجية (الالتهاب و التدمير العصبى) في نموذج الجرذان لمرض الزهايمر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Hany Hassan Abdelnaby , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 138 P. : |
| Other physical details | photographs ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Animal Behavior and Management |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study was designed to evaluate the ameliorating and protective effect of caffeine (CF), Chia extract (CH) and Lepidium Sativum extract (LS) on aluminum chloride (AlCl3) induced AD rat model. 128 adult Wistar male rats were allocated into 8 groups of 16 animals each, where control group (C) was supplied with normal tap water, while AD group was administered AlCl3 in drinking water at 200 mg/kg body weight. AD ameliorated groups with caffeine (CF-AD), chia (AD-CH) and LS (AD-LS) were exposed to AlCl3 alternatively with the ameliorating treatments in a day after day regime, while in CF, CH and LS groups rats were administered the different treatments alternatively with plan water. All groups received their respective treatments for 4 months after which behavioural analysis was performed including open field test (OFT) and elevated plus maze to assess anxiety-like behaviours, Y- maze test and novel object recognition test (NOR) to assess memory and learning abilities and forced swim test (FST) to evaluate the depression-like behaviour. After monitoring the behavioural activities, rats were decapitated, and their brains and hippocampus samples were collected for analysis of oxidative status (SOD, GSH, GSSG, MDA, 8OHdG, NO), metabolic dysfunction (ATP, PC, PS) and neurochemical profile (DA, DOPAC, HVA, 5-HT, 5-HIAA) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Alzheimer's disease |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antioxidants |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Chia seeds |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Said Ellethey , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kassem Gabr Aliraqi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mervat Mahmoud Kamel , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.02.Ph.D.2018.Em.E | 01010110077920000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.02.Ph.D.2018.Em.E | 01020110077920000 | 22.09.2023 | CD - Rom | 77920.CD |