MARC details
| 000 -LEADER |
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| fixed length control field |
02939cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190611s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
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| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.16.M.Sc.2018.Sh.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Shimaa Ahmed Zaki |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Synergistic therapeutic potential of dexamethasone and L-arginine on acetic acid-induced colitis in albino rats : |
| Remainder of title |
A histological and immunohistochemical study / |
| Statement of responsibility, etc. |
Shimaa Ahmed Zaki ; Supervised Hend Shafik Bassiouny , Noha Mohamed Afifi Amin , Marwa Mohamed Yousry |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
التآزر العلاجي المحتمل للديكساميثازون والأرجينين على إلتهاب القولون المحدث بحامض الخليك في الجرذان البيضاء دراسة هستولوجية وهستوكيميائية مناعية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Shimaa Ahmed Zaki , |
| Date of publication, distribution, etc. |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
203 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Histology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background:Dexamethasone (DEX) is widely used as the first line therapy of ulcerative colitis. However, long term glucocorticoids treatment often results in detrimental side effects. Recent studies suggested that L-arginine (Arg.) may be a promising supplement that maintains mucosal integrity and healing. Aim of the study:To evaluate the synergistic therapeutic effect of combined DEX and Arg. on acetic acid-induced colitis; monitored by histological, immunohistochemical and laboratory methods. Material & Methods: Twenty eight,12 weeks-old-male albino rats were divided into: group I (control), group II (Acetic acid (AA)-treated), group III (AA and DEX-treated), group IV (AA and Arg.-treated) and group V (AA, DEX and Arg.-treated). 2 ml of AA 4% was instilled intracolonic, once daily for 3 consecutive days. DEX was injected intraperitoneally, once daily for one week, at a dose of 2 mg/kg. Arg. was administrated orally, once daily for one week, at a dose of 100 mg. The proximal 3 cm of the descending colon were analyzed for studying expression ofiNOS, NO, TNF-Ü and IL-1Ý. The distal 3 cm of colonic specimens were stained with H&E, Alcian blue and immunohistochemical staining for COX-2. Morphometric measurement and statistical analysis were done. Results:AA-treated group sections revealed massive distortion of colonic wall architecture. Supplementation with DEX and Arg. could preserve the mucosal integrity and inflammatory profile |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Dexamethasone |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Induced colitis |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
L-arginine |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hend Shafik Bassiouny , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Marwa Mohamed Yousry , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Noha Mohamed Afifi Amin , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
