The proliferation effect of platelet-rich plasma on human dental pulp stem cells : (Record no. 72368)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02903cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032313.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190613s2017 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.12.M.Sc.2017.He.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Heba Shawky Helmi Abdelhamid |
| 245 14 - TITLE STATEMENT | |
| Title | The proliferation effect of platelet-rich plasma on human dental pulp stem cells : |
| Remainder of title | In vitro study / |
| Statement of responsibility, etc. | Heba Shawky Helmi Abdelhamid ; Supervised Mohamad Gad Abas , Ahmed Wael Abouzeid , Dina Sabry Abdelfattah |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير البلازما الغنية بالصفائح الدموية على تكاثر الخلايا الجذعية المستخرجة من لب الأسنان البشرية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Heba Shawky Helmi Abdelhamid , |
| Date of publication, distribution, etc. | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 127 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Biology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Dental pulp stem cells (DPSCs) are {u200E}considered an easily accessible source of mesenchymal {u200E}stem cells holding great promise for use in tissue repair and {u200E}regenerative medicine. In order for DPSCs to be used in {u200E}therapeutic clinical applications, issues like safely {u200E}enhancing culture expansion need to be addressed. {u200E}Objective: In this research, we aimed to assess the safety of {u200E}platelet rich plasma (PRP) as a promoter of proliferation in {u200E}comparison to routinely used animal derived supplements. {u200E}Methods: The effect of PRP on the proliferation of DPSCs {u200E}was assessed by MTT assay. Expression of stemness-{u200E}related genes OCT4 & INTGRIN1 was analyzed by real-{u200E}time quantitative PCR. DNA sequencing was performed {u200E}for OCT4 & INTGRIN1 genes to ensure that the isolated {u200E}DPSCs stem cell properties were not altered by the PRP {u200E}supplemented media. Results: At a concentration of 1% {u200E}with platelet count of 1.5 x 106/cm3, PRP was able to {u200E}significantly increase the proliferation rate while {u200E}maintaining the viability of DPSCs in comparison to {u200E}routinely used 15% FBS. Mesenchymal stem cell surface {u200E}markers expression (CD29, CD105) were not altered by {u200E}PRP supplementation. Moreover, PRP in cultures {u200E}significantly promoted expression of stemness markers {u200E}OCT4 & INTGRIN1 compared with 10% FBS |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Dental pulp stem cells |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Platelet rich plasma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Proliferation |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Wael Abouzeid , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dina Sabry Abdelfattah , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamad Gad Abas , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.12.M.Sc.2017.He.P | 01010110078402000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.12.M.Sc.2017.He.P | 01020110078402000 | 22.09.2023 | CD - Rom | 78402.CD |