Effect of certain antiepileptic drug(s) with low dose whole body gamma irradiation in modulating pentylenetetrazole-induced convulsions in rats / (Record no. 72618)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02601cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032321.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190702s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.Ph.D.2019.Di.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dina Mahmoud Lotfy Shaaban |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of certain antiepileptic drug(s) with low dose whole body gamma irradiation in modulating pentylenetetrazole-induced convulsions in rats / |
| Statement of responsibility, etc. | Dina Mahmoud Lotfy Shaaban ; Supervised Sanaa A. Kenawy , Seham H. M. Hassan , Marwa M. Safar |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تاثير احد الادوية المضادة للصرع او اكثر مع جرعة صغيرة من تعرض الجسم الكلى للاشعاع الجامى للحد من التشنجات المحدثه بالبنتيلين تيترازول في الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Dina Mahmoud Lotfy Shaaban , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 118 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present work was constructed to study the potential therapeutic effect of low dose gamma irradiation alone or combined with valproic acid or topiramate as antiepileptic drugs on an experimental model of acute convulsions induced by pentylenetetrazole in rats. Rats were classified into two sets each one consists of 5 groups. Set I includes groups related to valproic acid alone or combined with low dose whole body gamma irradiation. Set II includes groups related to topiramate alone or combined with low dose whole body gamma irradiation. After pentylenetetrazole injection, Racine{u2019} score, latency and duration of convulsions were observed for 30 min. Moreover, the brain hippocampi contents of biogenic amines (glutamate and GABA) as well as AKT/m-TOR signalling pathway assessment [protein kinase B (AKT), mammalian target of rapamycin (m-TOR), protein S6], caspase 3 relative gene expression was assessed, oxidative stress biomarkers ( MDA, GSH and NO) were examined. Brain hippocampi were also used for histopathological examination |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Low dose whole body gamma irradiation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Topiramate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Valproic acid |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa M. Safar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanaa A. Kenawy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Seham H.M. Hassan , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Asmaa |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.Ph.D.2019.Di.E | 01010110078528000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.Ph.D.2019.Di.E | 01020110078528000 | 22.09.2023 | CD - Rom | 78528.CD |