A molecular study of ABCB4 (MDR3) gene mutation in cholestatic disorders of infancy / (Record no. 72765)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02420cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032325.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190710s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.Ph.D.2019.Ne.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nevian Nabil Abbass |
| 245 12 - TITLE STATEMENT | |
| Title | A molecular study of ABCB4 (MDR3) gene mutation in cholestatic disorders of infancy / |
| Statement of responsibility, etc. | Nevian Nabil Abbass ; Supervised Hanaa Mostafa Elkaraksy , Mona Elsaid Elraziky , Sahar Abdelatty Sharaf |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | في أمراض الركود المرارى في الطفوله ABCB4 دراسة جزيئية عن تحور {uئآ٧ؤ}ين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Nevian Nabil Abbass , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 158 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Progressive familial intrahepatic cholestasis type 3 is caused by a genetic defect in the ABCB4 gene (also designated MDR3) located on chromosome 7. PFIC3 has wide variety of symptoms and usually progresses from chronic cholestasis with or without jaundice to portal hypertension and end stage liver disease. The aim of this study is to detect ABCB4 (MDR3) gene mutations as a cause of PFIC3 in infants with cholestasis.This cross sectional study was conducted at the Pediatric Hepatology Unit over a 3-year period from January 2013 till January 2016. Thirty cholestatic patients with high GGT with onset of symptoms in the first year of life were enrolled. All patients were subjected to full history and clinical examination. Laboratory tests were done in the form of complete blood count, liver function tests, alpha-1-antitrypsin level and TORCH screen when indicated. Abdominal ultrasound was done to all patients. All patients underwent liver biopsy and histopathology. Genetic sequencing was done to all patients with DNA extraction to be used for performing the PCR for ABCB4 gene study |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ABCB4 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MDR3 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | PFIC3 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanaa Mostafa Elkaraksy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Elsaid Elraziky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sahar Abdelatty Sharaf , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.Ph.D.2019.Ne.M | 01010110078604000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.Ph.D.2019.Ne.M | 01020110078604000 | 22.09.2023 | CD - Rom | 78604.CD |