MARC details
000 -LEADER |
fixed length control field |
02320cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
190716s2019 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.12.21.M.Sc.2019.No.R |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Noura Elhusseiny Bauomy Mohamed |
245 10 - TITLE STATEMENT |
Title |
Role of syndecan-1 in modulating the interaction between monocytes and breast cancer stem cells / |
Statement of responsibility, etc. |
Noura Elhusseiny Bauomy Mohamed ; Supervised Mona Mostafa Mohamed , Noha Ahmed Mahana , Sherif Abdelaziz Ibrahim |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
دور السينديكان-١ فى تعديل التفاعل بين الخلايا احادية النواة و الخلايا الجذعية لسرطان الثدى |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Noura Elhusseiny Bauomy Mohamed , |
Date of publication, distribution, etc. |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
81 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer and is characterized by a high infiltration of CD14+ monocytes. A growing body of evidence indicates that tumor-associated macrophages (TAMs) are classified into two major phenotypes, tumor inhibiting M1 and tumor promoting M2. The transmembrane heparan sulfate proteoglycan Syndecan-1 (Sdc-1) expression is induced in a variety of cell types during development and tumor progression and plays an essential role in regulation, recruitment and activation of monocytes in tumor microenvironment. We have recently shown that Sdc-1 is overexpressed in tumor tissue samples of IBC vs non-IBC. However, the role of Syndecan-1 in mediating macrophage polarization is still poorly studied. In the present study, we have employed siRNA approach to silence Syndecan-1 expression in the human breast cancer cell lines MDA-MB-231 (non-IBC) and SUM- 149 (IBC) cells |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Inflammatory breast cancer |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Syndecan-1 |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Tmor-associated macrophages and Monocytes |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mona Mostafa Mohamed , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Noha Ahmed Mahana , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Sherif Abdelaziz Ibrahim , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |