Efficacy of doxycycline in the treatment of early stages of mycosis fungoides : (Record no. 73003)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02577cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032332.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190720s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.Ph.D.2019.Ha.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hagar Elsayed Abdelghani Anter |
| 245 10 - TITLE STATEMENT | |
| Title | Efficacy of doxycycline in the treatment of early stages of mycosis fungoides : |
| Remainder of title | A randomized controlled trial / |
| Statement of responsibility, etc. | Hagar Elsayed Abdelghani Anter ; Supervised Mona R. E. Abdelhalim , Nesrin Samir Elkholy , Suzan Mohamed Shalaby |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | كفاءة عقار الدوكسيسيكلين فى علاج مرض الفطر الفطرانى - المراحل الأولية : |
| Remainder of title | تجربة عشوائية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Hagar Elsayed Abdelghani Anter , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 150 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerdogy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Mycosis fungoides (MF) is the most common type of primary cutaneous T cell lymphomas mostly resulting from defective T cell apoptosis. Doxycycline promoted apoptosis in different human malignant cell lines and in-vivo models. Objectives: To test for the therapeutic efficacy of doxycycline in comparison to PUVA in early stages of classic MF and its effect on the apoptosis of T lymphocytes. Methods: This randomized controlled trial (RCT) was conducted for 12 weeks. Thirty-six patients were randomized into either: doxycycline 200 mg daily (n=18) or PUVA (3 weekly sessions) (n=18). The primary outcome (therapeutic efficacy) was defined in terms of objective response rate (ORR) which was measured according to changes in the modified severity weighted assessment tool (mSWAT). Secondary outcomes included assessment of time to response (TTR) and changes in: the composite assessment of index lesion severity (CAILS), pruritus score, patient's satisfaction score (DLQI), serum Ý2 microglobulin level, serum LDH level, histopathology score and the immunohistochemical expression of CD3 and Bcl-2 |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Doxycycline |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mycosis fungoides |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Randomized controlled trial |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona R. E. Abdelhalim , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nesrin Samir Elkholy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Suzan Mohamed Shalaby , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.Ph.D.2019.Ha.E | 01010110078766000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.Ph.D.2019.Ha.E | 01020110078766000 | 22.09.2023 | CD - Rom | 78766.CD |