A pharmaceutical study on mosapride for intranasal administration / (Record no. 73081)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02144cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032334.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190727s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.10.M.Sc.2019.Re.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Reham Waheed Mahmoud Hammad |
| 245 12 - TITLE STATEMENT | |
| Title | A pharmaceutical study on mosapride for intranasal administration / |
| Statement of responsibility, etc. | Reham Waheed Mahmoud Hammad ; Supervised Nevine Shawky Abdelmalak , Randa Latif Aziz , Rania Abdelbaset Sanad |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة صيدلية علي عقار الموزابريد لاستخدامة عن طريق الانف |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Reham Waheed Mahmoud Hammad , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 229 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Industrial Pharmacy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Mosapride citrate (MOS) is a potent gastroprokinetic agent, used in the treatment of various gastrointestinal disorders caused by reduced gastrointestinal motility including gastroesophageal reflux disease (GERD). MOS would neither result in cardiac nor nervous adverse reactions due to selective stimulation of serotonin 5-HT4 receptors, without any considerable affinity for dopamine D2, 5-HT1, 5-HT2, or adrenergic receptors. Presently, available tablet dosage formulation of MOS is incapable to achieve the required clinical efficacy. Its short half-life (t1/2), intensive first-pass metabolism, poor solubility, and poor wettability lower its oral bioavailability to be 8-14%.This very low oral bioavailability restricts its use. So, the aim of this study was to improve the bioavailability MOS through intranasal administration |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mosapride citrate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nasal |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Xyloglucan |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nevine Shawky Abdelmalak , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Randa Latif Aziz , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania Abdelbaset Sanad , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Asmaa |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.10.M.Sc.2019.Re.P | 01010110078664000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.10.M.Sc.2019.Re.P | 01020110078664000 | 22.09.2023 | CD - Rom | 78664.CD |